[[Image:2nzj.png|left|200px|thumb|Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide [[2nzj]]]]
[[Image:2nzj.png|left|200px|thumb|Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide [[2nzj]]]]
{{STRUCTURE_3cbq| PDB=3cbq | SIZE=350| SCENE= |right|CAPTION=GTP-binding protein Rem2 complex with GDP (stick model) , ethylene glycol and Mg+2 ion (green) [[3cbq]] }}
{{Clear}}
'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell. They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: heterotrimeric G proteins and small GTPases. See details on GTP-binding protein LpeD in [[LepA]].
'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell. They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: heterotrimeric G proteins and small GTPases. See details on GTP-binding protein LpeD in [[LepA]].
{{Template:GPCR3sn6}}
<scene name='Template:GPCR3sn6/3sn6memrane/15'>An activated G protein-coupled receptor</scene> (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) ([[3sn6]]), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.
File:2nzj.pngCrystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide 2nzj
GTP-binding proteins or G proteins are transmitting signals outside the cell which cause changes within the cell. They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: heterotrimeric G proteins and small GTPases. See details on GTP-binding protein LpeD in LepA.
An activated G protein-coupled receptor (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) (3sn6), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.
3sn6 - human β-2 adrenergic receptor + cameloid antibody fragment bound by guanine nucleotide-binding protein G. This is the first structure of an activated G protein-coupled receptor in a complex with its G protein.
