CD44: Difference between revisions

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'''CD44''' is a glycoprotein involved in cell-cell interactions.  CD44 is a receptor of hyaluronic acid (HA).  CD44 undergoes post-translational modification.  Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.<ref>PMID:25195884</ref>
'''CD44''' is a glycoprotein involved in cell-cell interactions.  CD44 is a receptor of hyaluronic acid (HA).  CD44 undergoes post-translational modification.  Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.<ref>PMID:25195884</ref>
*<scene name='52/523368/Cv/2'>Binding site of CD44 hyaluronan-binding domain</scene> ([[2jcq]]).<ref>PMID:17293874</ref>
*<scene name='52/523368/Cv/3'>Binding site of CD44 hyaluronan-binding domain</scene> ([[2jcq]]).<ref>PMID:17293874</ref>


== Relevance ==
== Relevance ==

Revision as of 11:08, 29 November 2015

Structure of mouse CD44 hyaluronan-binding domain complex with hyaluronic acid (PDB code 2jca)

Drag the structure with the mouse to rotate

3D structures of CD44

Updated on 29-November-2015

2jcq, 4pz4 – hCD44 hyaluronan-binding domain – human
1poz, 2i83 - hCD44 hyaluronan-binding domain – NMR
2jcp - mCD44 hyaluronan-binding domain – mouse
2jcq, 2jcr - mCD44 hyaluronan-binding domain + 8-mer HA
4mrd, 4mre, 4mrf, 4mrg, 4mrh, 4np2, 4np3 - mCD44 hyaluronan-binding domain + inhibitor
4np3 - mCD44 hyaluronan-binding domain + tetrapeptide

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman