Dehalogenase: Difference between revisions
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<StructureSection load='2edc' size='340' side='right' caption='Structure of haloalkane dehalogenase complex with I- ion (purple) (PDB code [[2edc]]).' scene=''> | <StructureSection load='2edc' size='340' side='right' caption='Structure of haloalkane dehalogenase complex with I- ion (purple) (PDB code [[2edc]]).' scene=''> | ||
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== Function == | == Function == | ||
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• '''5-chloromuconolactone dehalogenase''' converts 5-chloromuconolactone to E-dienelactone.<br /> | • '''5-chloromuconolactone dehalogenase''' converts 5-chloromuconolactone to E-dienelactone.<br /> | ||
• '''Tetrachloroethene reductive dehalogenase''' catalyzes the conversion of trichloroethene, Cl- and acceptor to tetrachloroethene and reduced acceptor. | • '''Tetrachloroethene reductive dehalogenase''' catalyzes the conversion of trichloroethene, Cl- and acceptor to tetrachloroethene and reduced acceptor. | ||
== Relevance == | == Relevance == | ||
Haloalkane dehalogenase is tested for the biodegredation of toxic industrial by-products. | Haloalkane dehalogenase is tested for the biodegredation of toxic industrial by-products. Fluoroacetate dehalogenase is tested for the biodegredation of the poisonous fluroacetate which can kill livestock and is found in some plants in Australia, Africa and Central America. | ||
== Structural highlights == | == Structural highlights == | ||
In the fluoroacetate dehalogenase complex with halide, the iodide is seen in the active site cavity between two tryptophanes.<ref>PMID:8369276</ref> | |||
</StructureSection> | </StructureSection> | ||
