Factor XIII: Difference between revisions
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{{STRUCTURE_1ggt| PDB=1ggt | SIZE=300| SCENE=Factor_XIII/Cv/1 |right|CAPTION=Human Factor XIII dimer, [[1ggt]] }} | {{STRUCTURE_1ggt| PDB=1ggt | SIZE=300| SCENE=Factor_XIII/Cv/1 |right|CAPTION=Human Factor XIII dimer, [[1ggt]] }} | ||
== Function == | |||
[[Factor XIII]] (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide<ref>PMID:17842715</ref>. | [[Factor XIII]] (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide<ref>PMID:17842715</ref>. | ||
== Disease == | |||
FXIII deficiency causes internal bleeding. | |||
== 3D Structures of Factor XIII == | == 3D Structures of Factor XIII == | ||
