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| {{STRUCTURE_2fgh| PDB=2fgh | SCENE= |CAPTION=Gelsolin (GLS) dimer complex with ATP (red), [[2fgh]] }} | | {{STRUCTURE_1h1v| PDB=1h1v | SCENE= |CAPTION=Gelsolin (GLS) dimer complex with ATP (red), [[2fgh]] }} |
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Revision as of 09:21, 6 March 2016
File:3ffn.jpg
Template:STRUCTURE 1h1v
Function
Gelsolin (GLS) is a protein regulator of actin assembly and disassembly[1].
Structural highlights
The image at the top left corresponds to the human gelsolin (3ffn), it has dimeric form. It contains 6 homologous domains S1 to S6.
3D Structures of GLS
Updated on 06-March-2016
{"openlevels":0}
- GLS
- GLS domains S1-S3
- GLS domains S4-S6
- 1h1v - hGLS +actin
- 1nph - mGLS +Ca – mouse
- GLS domain S1
- 2ff3 - hGLS +N-WASP+actin
- 2ff6 - hGLS +Ciboulot domain 2+actin
- [1mdu]] - hGLS +chActin – chicken
- 1d4x - hGLS +CeActin+Mg-ATP – Caenorhabditis elegans
- 1esv - hGLS +rActin+latrunculin – rabbit
- 1eqy - hGLS +rActin
- 1yvn - hGLS +yActin (mutant) – yeast
- 1yag - hGLS +yActin
- 1t44 - hGLS/thymosin β-4 C-terminal fusion+rActin
- 1kcq – hGLS +Cd
- 1c0f, 1mdu, 1nmd - hGLS + Actin+Ca-ATP
- 1c0g, 1dej - hGLS +Actin (mutant)
- 3a5l, 3a5m, 3a5n, 3a5o - hGLS (mutant)+Actin (mutant)
- 3ci5, 3cip, 1nlv – DdGLS +actin - Dictyostelium discoideum
- 1nm1 - DdGLS +actin+Mg-ATP
- 3cjb - rGLS +rActin
- 3cjc - rGLS +rActin+DNAse I
- 4cbu, 4cbw, 4cbx - mGLS +actin+Ca+ATP
- GLS C-terminal
- ↑ Sun HQ, Yamamoto M, Mejillano M, Yin HL. Gelsolin, a multifunctional actin regulatory protein. J Biol Chem. 1999 Nov 19;274(47):33179-82. PMID:10559185
References
proteopedia link
