User:John S. de Banzie/Sandbox 4: Difference between revisions
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The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6). | The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6). | ||
Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs. | Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals secondary structure and extensive base pairing between the U4 and U6 snRNAs. | ||
The U2 snRNP <scene name='72/726441/Dockscene/1'>binds to the region </scene>highlighted in blue in this view. The U1 snRNP binds to the | The U2 snRNP <scene name='72/726441/Dockscene/1'>binds to the region</scene> highlighted in blue in this view. The U1 snRNP binds to the U2 snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome. | ||
For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>. | For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||