4e19

Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1

spinqualitylabelsall models 4e19, resolution 1.41Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4e19 is a 2 chain structure with sequence from Halsa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MN Gene: VNG_0255C (HALSA) Activity: Ribonuclease H, with EC number 3.1.26.4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [RNH_HALSA] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant. See Also Temp

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