4dyu: Difference between revisions
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==The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10== | ==The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10== | ||
<StructureSection load='4dyu' size='340' side='right' caption='[[4dyu]], [[Resolution|resolution]] 2.75Å' scene=''> | <StructureSection load='4dyu' size='340' side='right'caption='[[4dyu]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4dyu]] is a 12 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4dyu]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_KIM10+ Yersinia pestis KIM10+]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DYU FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dyu OCA], [https://pdbe.org/4dyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dyu RCSB], [https://www.ebi.ac.uk/pdbsum/4dyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dyu ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/DPS_YERPE DPS_YERPE]] During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.[HAMAP-Rule:MF_01441] | ||
==See Also== | ==See Also== | ||
*[[Ferritin|Ferritin]] | *[[Ferritin 3D structures|Ferritin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Yersinia pestis KIM10+]] | ||
[[Category: | [[Category: Anderson WF]] | ||
[[Category: Gu | [[Category: Gu M]] | ||
[[Category: Joachimiak | [[Category: Joachimiak A]] | ||
[[Category: Kwon | [[Category: Kwon K]] | ||
[[Category: Tan | [[Category: Tan K]] | ||
Revision as of 08:44, 21 September 2022
The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10
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