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==Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312==
==Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312==
<StructureSection load='4ls1' size='340' side='right' caption='[[4ls1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4ls1' size='340' side='right'caption='[[4ls1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ls1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LS1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LS1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ls1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LS1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LS1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3X2:2-[(E)-{2-[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]HYDRAZINYLIDENE}METHYL]BENZOIC+ACID'>3X2</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3X2:2-[(E)-{2-[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]HYDRAZINYLIDENE}METHYL]BENZOIC+ACID'>3X2</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ls0|4ls0]], [[4ls2|4ls2]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ls0|4ls0]], [[4ls2|4ls2]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DHODH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ls1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ls1 OCA], [http://pdbe.org/4ls1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ls1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ls1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ls1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ls1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ls1 OCA], [http://pdbe.org/4ls1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ls1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ls1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ls1 ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Li, H]]
[[Category: Li, H]]
[[Category: Ren, X]]
[[Category: Ren, X]]

Revision as of 09:29, 3 April 2019

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312

4ls1, resolution 2.20Å

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