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==crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin==
==crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin==
<StructureSection load='3sfu' size='340' side='right' caption='[[3sfu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3sfu' size='340' side='right'caption='[[3sfu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3sfu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Murine_norovirus_1 Murine norovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SFU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3sfu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Murine_norovirus_1 Murine norovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SFU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RBV:1-(BETA-D-RIBOFURANOSYL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE'>RBV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RBV:1-(BETA-D-RIBOFURANOSYL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE'>RBV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nah|3nah]], [[3nai|3nai]], [[3qid|3qid]], [[3sfg|3sfg]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3nah|3nah]], [[3nai|3nai]], [[3qid|3qid]], [[3sfg|3sfg]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RdRp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=223997 Murine norovirus 1])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RdRp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=223997 Murine norovirus 1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfu OCA], [http://pdbe.org/3sfu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sfu RCSB], [http://www.ebi.ac.uk/pdbsum/3sfu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfu OCA], [https://pdbe.org/3sfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sfu RCSB], [https://www.ebi.ac.uk/pdbsum/3sfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfu ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
*[[Rebetol|Rebetol]]
*[[Ribavirin|Ribavirin]]
*[[Ribavirin (1-β-D-ribofuranosyl-1H-1%2C2%2C4-triazole-3-carboxamide)|Ribavirin (1-β-D-ribofuranosyl-1H-1%2C2%2C4-triazole-3-carboxamide)]]
*[[Ribavirin1|Ribavirin1]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Murine norovirus 1]]
[[Category: Murine norovirus 1]]
[[Category: Alam, I]]
[[Category: Alam, I]]

Revision as of 07:54, 29 June 2022

crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin

3sfu, resolution 2.50Å

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