Sphingomyelinase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1zwx' size='350' side='right' caption='Sphingomyelinase complex with glycerol and phosphate ion (PDB entry [[21zwx])' scene=''> | |||
== Function == | == Function == | ||
'''Sphingomyelinase''' (SMase) or '''sphingomyelin phosphodiesterase''' is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide<ref>PMID:11001563</ref>. The SMase is classified into 5 types according to their pH dependence and cation dependence. | '''Sphingomyelinase''' (SMase) or '''sphingomyelin phosphodiesterase''' is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide<ref>PMID:11001563</ref>. The SMase is classified into 5 types according to their pH dependence and cation dependence. | ||
| Line 6: | Line 6: | ||
== Disease == | == Disease == | ||
Mutations in acid SMase are found in patients with Niemann-Pick disease<ref>PMID:17011332</ref>. | Mutations in acid SMase are found in patients with Niemann-Pick disease<ref>PMID:17011332</ref>. | ||
</StructureSection> | |||
==3D structures of sphingomyelinase== | ==3D structures of sphingomyelinase== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
Revision as of 09:58, 3 September 2017
| ||||||||||||
3D structures of sphingomyelinase
Updated on 03-September-2017
