DnaA: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load=' | <StructureSection load='' size='350' side='right' scene='50/509255/Cv/1' caption='E. coli DnaA complex with DNA ([[1j1v]])'> | ||
'''DnaA''' activates initiation of DNA replication in prokaryotes. DnaA promotes the unwinding of the DNA helix. The cellular concentration of DnaA determines the initiation of DNA replication. Active DnaA is bound to ATP. DnaA binds to DNA at a specific 9 base pair DnaA box in oriC (origin of replication sequence). <ref>PMID:17435790</ref> | '''DnaA''' activates initiation of DNA replication in prokaryotes. DnaA promotes the unwinding of the DNA helix. The cellular concentration of DnaA determines the initiation of DNA replication. Active DnaA is bound to ATP. DnaA binds to DNA at a specific 9 base pair DnaA box in oriC (origin of replication sequence). <ref>PMID:17435790</ref> | ||
Revision as of 06:55, 20 October 2017
| ||||||||||||
3D structures of DnaA
Updated on 20-October-2017
1j1v – AaDnaA + ADP – Aquifex aeolicus
Molecular Playground/DNA replication initiator DnaA - AaDnaA + AMPPCP
3r8f - AaDnaA DNA binding domain + DNA
1j1v – EcDnaA DNA binding domain + DNA – Escherichia coli
2e0g - EcDnaA N terminal – NMR
2jmp - DnaA N terminal – Mycoplasma genitalium – NMR
2z4r, 2z4s - DnaA domain III – Thermotoga maritima
2wp0 - DnaA N terminal + HOBA – Helicobacter pylori
3pvp, 3pvv - DnaA DNA binding domain + DNA – Mycobacterium tuberculosis
