6bsz: Difference between revisions
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==Human mGlu8 Receptor complexed with glutamate== | ==Human mGlu8 Receptor complexed with glutamate== | ||
<StructureSection load='6bsz' size='340' side='right' caption='[[6bsz]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='6bsz' size='340' side='right'caption='[[6bsz]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6bsz]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6bsz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BSZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BSZ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand= | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bsz OCA], [https://pdbe.org/6bsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bsz RCSB], [https://www.ebi.ac.uk/pdbsum/6bsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bsz ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GRM8_HUMAN GRM8_HUMAN] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6bsz" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6bsz" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Metabotropic glutamate receptor 3D structures|Metabotropic glutamate receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Atwell | [[Category: Large Structures]] | ||
[[Category: Chen | [[Category: Atwell S]] | ||
[[Category: Hao | [[Category: Chen Q]] | ||
[[Category: Ho | [[Category: Hao J]] | ||
[[Category: Monn | [[Category: Ho JD]] | ||
[[Category: Schkeryantz | [[Category: Monn JA]] | ||
[[Category: Vargas | [[Category: Schkeryantz JM]] | ||
[[Category: Wang | [[Category: Vargas MC]] | ||
[[Category: Zhang | [[Category: Wang J]] | ||
[[Category: Zhang A]] | |||
Revision as of 10:31, 15 February 2023
Human mGlu8 Receptor complexed with glutamate
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