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| ==Golgi alpha-mannosidase II complex with Noeuromycin== | | ==Golgi alpha-mannosidase II complex with Noeuromycin== |
| <StructureSection load='2alw' size='340' side='right' caption='[[2alw]], [[Resolution|resolution]] 1.86Å' scene=''> | | <StructureSection load='2alw' size='340' side='right'caption='[[2alw]]' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ALW FirstGlance]. <br> | | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ALW FirstGlance]. <br> |
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [https://pdbe.org/2alw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [https://www.ebi.ac.uk/pdbsum/2alw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr> |
| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hty|1hty]], [[1hww|1hww]], [[1hxk|1hxk]], [[1ps2|1ps2]], [[1qwn|1qwn]], [[1qx1|1qx1]], [[1r33|1r33]], [[1r34|1r34]], [[1tqs|1tqs]], [[1tqt|1tqt]], [[1tqu|1tqu]], [[1tqw|1tqw]]</td></tr>
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| <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://pdbe.org/2alw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr> | |
| </table> | | </table> |
| == Function ==
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| [[http://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
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| == Evolutionary Conservation == | | == Evolutionary Conservation == |
| [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| ==See Also== | | ==See Also== |
| *[[Mannosidase|Mannosidase]] | | *[[Mannosidase 3D structures|Mannosidase 3D structures]] |
| __TOC__ | | __TOC__ |
| </StructureSection> | | </StructureSection> |
| [[Category: Drome]] | | [[Category: Large Structures]] |
| [[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
| | [[Category: Bols MB]] |
| [[Category: Bols, M B]] | | [[Category: Kuntz DA]] |
| [[Category: Kuntz, D A]] | | [[Category: Liu H]] |
| [[Category: Liu, H]] | | [[Category: Rose DR]] |
| [[Category: Rose, D R]] | |
| [[Category: Glycosyl hydrolase family 38]]
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| [[Category: Hydrolase]]
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