5qc2: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,329,557 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,329,557 edits
No edit summary
Line 1: Line 1:


==Crystal structure of human Cathepsin-S with bound ligand==
==Crystal structure of human Cathepsin-S with bound ligand==
<StructureSection load='5qc2' size='340' side='right' caption='[[5qc2]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
<StructureSection load='5qc2' size='340' side='right'caption='[[5qc2]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5qc2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QC2 FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QC2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BQP:2-[1-(cyclohexylmethyl)piperidin-4-yl]-1-{3-[3-{[2-(4-fluoropiperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-1-(3-hydroxypropyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one'>BQP</scene></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qc2 OCA], [https://pdbe.org/5qc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qc2 RCSB], [https://www.ebi.ac.uk/pdbsum/5qc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qc2 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qc2 OCA], [http://pdbe.org/5qc2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qc2 RCSB], [http://www.ebi.ac.uk/pdbsum/5qc2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qc2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.


==See Also==
==See Also==
*[[Cathepsin|Cathepsin]]
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cathepsin S]]
[[Category: Large Structures]]
[[Category: Human]]
[[Category: Ameriks MK]]
[[Category: Ameriks, M K]]
[[Category: Bembenek SD]]
[[Category: Bembenek, S D]]
[[Category: Burley SK]]
[[Category: Burley, S K]]
[[Category: Mirzadegan T]]
[[Category: Mirzadegan, T]]
[[Category: Shao C]]
[[Category: Shao, C]]
[[Category: Yang H]]
[[Category: Yang, H]]
[[Category: Cathepsin s]]
[[Category: D3r]]
[[Category: Hydrolase]]
[[Category: Ligand docking]]

Revision as of 14:05, 17 November 2021

Crystal structure of human Cathepsin-S with bound ligand

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=5qc2&oldid=3478907"