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==Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978==
==Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978==
<StructureSection load='2qs9' size='340' side='right' caption='[[2qs9]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
<StructureSection load='2qs9' size='340' side='right'caption='[[2qs9]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QS9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QS9 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [http://pdbe.org/2qs9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [http://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qs9 ProSAT], [http://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [https://pdbe.org/2qs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [https://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qs9 ProSAT], [https://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RBBP9_HUMAN RBBP9_HUMAN]] May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.  
[[https://www.uniprot.org/uniprot/RBBP9_HUMAN RBBP9_HUMAN]] May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Retinoblastoma-binding protein|Retinoblastoma-binding protein]]
*[[Retinoblastoma-binding protein 3D structures|Retinoblastoma-binding protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Acton, T B]]
[[Category: Acton, T B]]
[[Category: Chen, C X]]
[[Category: Chen, C X]]

Revision as of 08:31, 25 June 2021

Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978

2qs9, resolution 1.72Å

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