Gephyrin: Difference between revisions

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<StructureSection load='4u91' size='340' side='right' caption='Rat gephyrin E domain (grey) complex with glycine receptor peptide (pink), acetate and Ca+2 ion (green) (PDB code [[4u91]])' scene=''>
<StructureSection load='4u91' size='340' side='right' caption='Rat gephyrin E domain (grey) complex with glycine receptor peptide (green), acetate and Ca+2 ion (green) (PDB code [[4u91]])' scene=''>


== Function ==
== Function ==
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== Relevance ==
== Relevance ==


Abnormal accumulation of Gep are highly correlated with the neuropathologic diagnosos of Alzheimer Disease<ref>PMID:24128675</ref>.
Abnormal accumulation of Gep are highly correlated with the neuropathologic diagnosis of Alzheimer Disease<ref>PMID:24128675</ref>.


== Structural highlights ==
== Structural highlights ==

Revision as of 09:26, 29 October 2018

Rat gephyrin E domain (grey) complex with glycine receptor peptide (green), acetate and Ca+2 ion (green) (PDB code 4u91)

Drag the structure with the mouse to rotate

3D structures of gephyrin

Updated on 29-October-2018

2fu3, 5erq, 4pd0 - rGeph E domain 318-736 - rat
2fts, 4pd1, 1t3e, 4u91 - rGeph E domain + glycine receptor peptide
4tk1, 4tk2, 4tk3, 4tk4, 4u90 - rGeph E domain + GABA receptor peptide
5ers - rGeph E domain + AMP
5ert, 5err - rGeph E domain + ADP
5eru - rGeph E domain + ADP + Mo + MoO4
5erv - rGeph E domain + ADP + W + WO4
1thc - rGeph N terminal

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky