Colony-stimulating factor receptor: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Colony-stimulating factor receptor''' (CSFR) are binding the [[Col... |
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
== Function == | == Function == | ||
'''Colony-stimulating factor receptor''' (CSFR) are binding the [[Colony-stimulating factor]]s and thus mediating the lineage-specific growth of cells of the mononuclear phagocytes series as bone marrow-derived precursors of monocytes and macrophages<ref>PMID:2852667</ref>. | '''Colony-stimulating factor receptor''' (CSFR) are binding the [[Colony-stimulating factor]]s and thus mediating the lineage-specific growth of cells of the mononuclear phagocytes series as bone marrow-derived precursors of monocytes and macrophages<ref>PMID:2852667</ref>. The '''granulocyte colony stimulating factor receptor''' (G-CSFR) participates in the development, survival and activation of neutrophilic granulocytes and in the development of other myeloid lineages. | ||
== Disease == | == Disease == | ||
Mutations in G-CSFR were found in patients with severe congenital neutropenia<ref>PMID:9001427</ref>. | |||
== Relevance == | == Relevance == | ||
Revision as of 10:37, 15 November 2018
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3D structures of colony-stimulating factor receptor
Updated on 15-November-2018
