Colony-stimulating factor: Difference between revisions
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The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>. | The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>. | ||
==3D structures of colony-stimulating factor== | |||
[[Colony-stimulating factor 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
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**[[2gmf]], [[3uf2]] - hM-CSF - human<br /> | **[[2gmf]], [[3uf2]] - hM-CSF - human<br /> | ||
**[[5lxf]] - hM-CSF (mutant)<br /> | **[[5lxf]] - hM-CSF (mutant)<br /> | ||
**[[4adq]], [[4adf]] - hM-CSF + BARF1<br /> | **[[4adq]], [[4adf]], [[4fa8]] - hM-CSF + BARF1<br /> | ||
**[[3uez]] - hM-CSF (mutant) + BARF1<br /> | **[[3uez]] - hM-CSF (mutant) + BARF1<br /> | ||
**[[4wrm]], [[4wrl]] - hM-CSF + CSF receptor<br /> | **[[4wrm]], [[4wrl]] - hM-CSF + CSF receptor<br /> | ||
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*Granulocyte colony stimulating factor | *Granulocyte colony stimulating factor | ||
**[[1rhg]] - hG-CSF <br /> | **[[1rhg]] - hG-CSF <br /> | ||
**[[1gnc]] - hG-CSF - NMR<br /> | **[[1gnc]] - hG-CSF - NMR<br /> | ||
**[[5gw9]] - hG-CSF (mutant)<br /> | **[[5gw9]], [[5zo6]] - hG-CSF (mutant)<br /> | ||
**[[2d9q]], [[1pgr]], [[1cd9]] - hG-CSF + CSF receptor<br /> | **[[2d9q]], [[1pgr]], [[1cd9]] - hG-CSF + CSF receptor<br /> | ||
**[[1bgc]] - G-CSF - bovine<br /> | |||
**[[1bgd]], [[1bge]] - G-CSF - dog<br /> | |||
**[[1gcf]], [[1cto]] - mG-CSF C-terminal of LBD - NMR<br /> | **[[1gcf]], [[1cto]] - mG-CSF C-terminal of LBD - NMR<br /> | ||
}} | }} | ||
