Im7: Difference between revisions
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Im7 is a [[Colicin Immunity Protein]] that binds to the nuclease domain of [[Colicin E7]], in order to protect the cell producing the [[Colicin]] from the [[DNase Activity]]. When it binds to colicin E7 it physically blocks off the major dsDNA binding sites<ref> PMID: 14962381 </ref>. | Im7 is a [[Colicin Immunity Protein]] that binds to the nuclease domain of [[Colicin E7]], in order to protect the cell producing the [[Colicin]] from the [[DNase Activity]]. When it binds to colicin E7 it physically blocks off the major dsDNA binding sites<ref> PMID: 14962381 </ref>. | ||
<Structure load='7cei' size='350' frame='true' align='right' caption='' /> | <Structure load='7cei' size='350' frame='true' align='right' caption='Im7 (grey) complex with colicin E7 (green) and Zn+2 ion (grey) (PDB code 7cei]])' /> | ||
This structure shows the <scene name='Im7/Im7/1'>Immunity protein</scene> bound to the <scene name='Im7/Cole7c/1'>ColE7 cytotoxic domain</scene>. | This structure shows the <scene name='Im7/Im7/1'>Immunity protein</scene> bound to the <scene name='Im7/Cole7c/1'>ColE7 cytotoxic domain</scene>. | ||
