6fzt: Difference between revisions

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'''Unreleased structure'''


The entry 6fzt is ON HOLD  until Paper Publication
==Crystal structure of Smad8_9-MH1 bound to the GGCGC site.==
 
<StructureSection load='6fzt' size='340' side='right'caption='[[6fzt]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
Authors: Kaczmarska, Z., Marquez, J.A., Macias, M.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6fzt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FZT FirstGlance]. <br>
Description: Crystal structure of Smad8_9-MH1 bound to the GGCGC site.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fzt OCA], [http://pdbe.org/6fzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fzt RCSB], [http://www.ebi.ac.uk/pdbsum/6fzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fzt ProSAT]</span></td></tr>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/SMAD9_HUMAN SMAD9_HUMAN]] Heritable pulmonary arterial hypertension. The disease may be caused by mutations affecting the gene represented in this entry.  
== Function ==
[[http://www.uniprot.org/uniprot/SMAD9_HUMAN SMAD9_HUMAN]] Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).  
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Kaczmarska, Z]]
[[Category: Kaczmarska, Z]]
[[Category: Marquez, J.A]]
[[Category: Macias, M J]]
[[Category: Macias, M.J]]
[[Category: Marquez, J A]]
[[Category: Dna complex]]
[[Category: Smad]]
[[Category: Transcription]]
[[Category: Transcription factor]]