Gelsolin: Difference between revisions

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GLS contains 6 homologous domains S1 to S6.  The human GLS domains span residues: 15-135, 136-248, 249-367, 394-513, 514-619 and 620-734. <scene name='41/410297/Cv/6'>S4-S6 are shown</scene>.  The <scene name='41/410297/Cv/7'>binding site of Ca+2 ion includes Glu, Asp and 2 carbonyl oxygens</scene><ref>PMID:12460571</ref>.
GLS contains 6 homologous domains S1 to S6.  The human GLS domains span residues: 15-135, 136-248, 249-367, 394-513, 514-619 and 620-734. <scene name='41/410297/Cv/6'>S4-S6 are shown</scene>.  The <scene name='41/410297/Cv/7'>binding site of Ca+2 ion includes Glu, Asp and 2 carbonyl oxygens</scene><ref>PMID:12460571</ref>.
== 3D Structures of gelsolin ==
[[3D Structures of gelsolin]]
</StructureSection>
</StructureSection>
== 3D Structures of GLS ==
== 3D Structures of gelsolin ==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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**[[3ffn]] – hGLS – human <br />
**[[3ffn]] – hGLS – human <br />
**[[6jeg]], [[6jeh]], [[6jco]] - hGLS (mutant) <br />
**[[2fgh]] – hoGLS+ATP – horse <br />
**[[2fgh]] – hoGLS+ATP – horse <br />
**[[1d0n]] - hoGLS <br />
**[[1d0n]] - hoGLS <br />
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* GLS domain S1 residues 51-178
* GLS domain S1 residues 51-178


**[[5zz0]] – hGLS <br />
**[[5h3m]], [[5h3n]] – hGLS – NMR<br />
**[[5h3m]], [[5h3n]] – hGLS – NMR<br />
**[[2ff3]] - hGLS +N-WASP+actin<br />
**[[2ff3]] - hGLS +N-WASP+actin<br />
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**[[3cjb]] - rGLS +rActin<br />  
**[[3cjb]] - rGLS +rActin<br />  
**[[3cjc]] - rGLS +rActin+DNAse I<br />
**[[3cjc]] - rGLS +rActin+DNAse I<br />
**[[4cbu]], [[4cbw]], [[4cbx]], [[5mvv]] - mGLS +actin+Ca+ATP<br />
**[[4cbu]], [[4cbw]], [[4cbx]], [[5mvv]], [[6i4d]], [[6i4e]], [[6i4f]], [[6i4g]], [[6i4h]], [[6i4i]], [[6i4j]], [[6i4k]], [[6i4l]], [[6i4m]] - mGLS +actin+ nucleotide<br />


*GLS S2 residues 178-293
*GLS S2 residues 178-293


**[[5fae]], [[5faf]], [[5o2z]] - hGLS (mutant) <br />
**[[5fae]], [[5faf]], [[5o2z]] - hGLS (mutant) <br />
**[[4s10]] - hGLS (mutant) + antibody<br />
**[[4s10]], [[6h1f]] - hGLS (mutant) + antibody<br />


* GLS domains S1-S3 residues 52-426
* GLS domains S1-S3 residues 52-426