6nie: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6nie is ~~ON HOLD until Dec 27 2020~~

==BesD with Fe(II), chloride, and alpha-ketoglutarate==

~~Authors~~: ~~Neugebauer~~, M.E., ~~Chang~~, M.C.Y.

== Structural highlights ==

<table><tr><td colspan='2'>[[6nie]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NIE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NIE FirstGlance]. <br>

~~Description~~: ~~BesD with Fe(II)~~, ~~chloride, and alpha~~-~~ketoglutarate~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nie OCA], [http://pdbe.org/6nie PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nie RCSB], [http://www.ebi.ac.uk/pdbsum/6nie PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nie ProSAT]</span></td></tr>

[[Category: Chang, M.C.Y]]

</table>

[[Category: Neugebauer, M.E]]

== Function ==

[[http://www.uniprot.org/uniprot/BESD_STREN BESD_STREN]] Involved in the biosynthesis of terminal alkyne-containing amino acids produced as antibiotics by S.cattleya. Catalyzes the chlorination of L-lysine at the C4 position, leading to the production of 4-chloro-L-lysine.<ref>PMID:30867596</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Chang, M C.Y]]

[[Category: Neugebauer, M E]]

[[Category: Biosynthetic protein]]

[[Category: Halogenase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6nie is ON HOLD  until Dec 27 2020
+==BesD with Fe(II), chloride, and alpha-ketoglutarate==
+<StructureSection load='6nie' size='340' side='right'caption='[[6nie]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-Authors: Neugebauer, M.E., Chang, M.C.Y.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6nie]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NIE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NIE FirstGlance]. <br>
-Description: BesD with Fe(II), chloride, and alpha-ketoglutarate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nie OCA], [http://pdbe.org/6nie PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nie RCSB], [http://www.ebi.ac.uk/pdbsum/6nie PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nie ProSAT]</span></td></tr>
-[[Category: Chang, M.C.Y]]
+</table>
-[[Category: Neugebauer, M.E]]
+== Function ==
+[[http://www.uniprot.org/uniprot/BESD_STREN BESD_STREN]] Involved in the biosynthesis of terminal alkyne-containing amino acids produced as antibiotics by S.cattleya. Catalyzes the chlorination of L-lysine at the C4 position, leading to the production of 4-chloro-L-lysine.<ref>PMID:30867596</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Chang, M C.Y]]
+[[Category: Neugebauer, M E]]
+[[Category: Biosynthetic protein]]
+[[Category: Halogenase]]