4z53: Difference between revisions

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<StructureSection load='4z53' size='340' side='right'caption='[[4z53]], [[Resolution|resolution]] 3.26&Aring;' scene=''>
<StructureSection load='4z53' size='340' side='right'caption='[[4z53]], [[Resolution|resolution]] 3.26&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4z53]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z53 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4z53]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z53 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR6:TROVAFLOXACIN'>TR6</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR6:TROVAFLOXACIN'>TR6</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4koe|4koe]], [[4pxp|4pxp]], [[3rad|3rad]], [[3rae|3rae]], [[3raf|3raf]], [[3ksb|3ksb]], [[3ksa|3ksa]], [[4i3h|4i3h]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z53 OCA], [https://pdbe.org/4z53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z53 RCSB], [https://www.ebi.ac.uk/pdbsum/4z53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z53 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">parC, SP_0855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z53 OCA], [http://pdbe.org/4z53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z53 RCSB], [http://www.ebi.ac.uk/pdbsum/4z53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z53 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
[https://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [https://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>  


==See Also==
==See Also==
*[[Topoisomerase|Topoisomerase]]
*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Strpn]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: Crevel, I M.T]]
[[Category: Crevel IM-T]]
[[Category: Fisher, L M]]
[[Category: Fisher LM]]
[[Category: Laponogov, I]]
[[Category: Laponogov I]]
[[Category: Pan, X S]]
[[Category: Pan X-S]]
[[Category: Sanderson, M R]]
[[Category: Sanderson MR]]
[[Category: Selvarajah, J]]
[[Category: Selvarajah J]]
[[Category: Veselkov, D A]]
[[Category: Veselkov DA]]
[[Category: Cleavage complex]]
[[Category: Dna]]
[[Category: Isomerase]]
[[Category: Quinolone]]
[[Category: Topo iv]]

Revision as of 07:39, 10 May 2023

Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae

4z53, resolution 3.26Å

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