6tza: Difference between revisions
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The | ==CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant== | ||
<StructureSection load='6tza' size='340' side='right'caption='[[6tza]], [[Resolution|resolution]] 7.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6tza]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TZA FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tza OCA], [http://pdbe.org/6tza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tza RCSB], [http://www.ebi.ac.uk/pdbsum/6tza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tza ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/IST1_HUMAN IST1_HUMAN]] Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.<ref>PMID:19129479</ref> <ref>PMID:19129480</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Frost, A]] | |||
[[Category: Nguyen, H C]] | |||
[[Category: Escrt-iii]] | |||
[[Category: Lipid binding protein]] | |||
[[Category: Membrane remodeling]] | |||
[[Category: Membrane-bound protein filament]] | |||
Revision as of 06:56, 8 April 2020
CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant
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