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| **[[3ltq]] - hIL-1 β residues 117-269 <BR /> | | **[[3ltq]] - hIL-1 β residues 117-269 <BR /> |
| **[[3pok]] - hIL-1 β residues 117-269 (mutant) <BR /> | | **[[3pok]] - hIL-1 β residues 117-269 (mutant) <BR /> |
| | **[[6y8i]], [[6y8m]] - hIL-1 β residues 117-269 + pyridine derivative<BR /> |
| **[[1itb]] - hIL-1 β + IL-1 receptor 1 extracellular domain<BR /> | | **[[1itb]] - hIL-1 β + IL-1 receptor 1 extracellular domain<BR /> |
| **[[3o4o]] - hIL-1 β + IL-1 receptor 2 + IL-1 receptor accessory protein<BR /> | | **[[3o4o]] - hIL-1 β + IL-1 receptor 2 + IL-1 receptor accessory protein<BR /> |
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| **[[1jli]] – hIL-3 (mutant) – NMR<BR /> | | **[[1jli]] – hIL-3 (mutant) – NMR<BR /> |
| | **[[6nmy]] – hIL-3 + IL-3 receptor α + cytokine receptor common subunit β<BR /> |
| **[[5uv8]], [[5uwc]] – hIL-3 (mutant) + IL-3 receptor α<BR /> | | **[[5uv8]], [[5uwc]] – hIL-3 (mutant) + IL-3 receptor α<BR /> |
| **[[2l3o]] – mIL-3 residues 33-156 (mutant) - NMR | | **[[2l3o]] – mIL-3 residues 33-156 (mutant) - NMR |
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| *IL-8 | | *IL-8 |
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| **[[3il8]], [[5d14]], [[4xdx]] – hIL-8 residues 28-99<BR /> | | **[[6n2u]] – hIL-8 <BR /> |
| **[[1il8]], [[2il8]], [[5wdz]] – hIL-8 - NMR<BR /> | | **[[1il8]], [[2il8]], [[5wdz]] – hIL-8 - NMR<BR /> |
| **[[1qe6]], [[1icw]] – hIL-8 (mutant) <BR /> | | **[[1qe6]], [[1icw]] – hIL-8 (mutant) <BR /> |
| **[[1ikl]], [[1ikm]] - hIL-8 (mutant) - NMR<BR /> | | **[[1ikl]], [[1ikm]] - hIL-8 (mutant) - NMR<BR /> |
| | **[[3il8]], [[5d14]], [[4xdx]] – hIL-8 residues 28-99<BR /> |
| **[[1rod]] - hIL-8/melanoma growth stimulating protein – NMR<br /> | | **[[1rod]] - hIL-8/melanoma growth stimulating protein – NMR<br /> |
| **[[1ilp]], [[1ilq]] - hIL-8 + IL-8 receptor peptide | | **[[1ilp]], [[1ilq]] - hIL-8 + IL-8 receptor peptide |
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| **[[5mxa]] - hIL-12 β + hIL- 23 α<br /> | | **[[5mxa]] - hIL-12 β + hIL- 23 α<br /> |
| **[[5mj3]], [[5mj4]] - hIL-12 β + hIL-23 α + alphabody MB3<br /> | | **[[5mj3]], [[5mj4]] - hIL-12 β + hIL-23 α + alphabody MB3<br /> |
| **[[3qwr]] - hIL-12 β + hIL- 23 α + adnectin | | **[[3qwr]] - hIL-12 β + hIL- 23 α + adnectin<br /> |
| | **[[6uib]] - hIL-12 β + hIL- 23 α + peptide<br /> |
| | **[[6sff]] - mIL-12 β <br /> |
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| *IL-13 | | *IL-13 |
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| **[[5vb9]] - hIL-17A + peptide inhibitor<BR /> | | **[[5vb9]] - hIL-17A + peptide inhibitor<BR /> |
| **[[5hi5]], [[5hi4]], [[5hi3]], [[5hhx]], [[5hhv]] - hIL-17A + peptide inhibitor + antibody<BR /> | | **[[5hi5]], [[5hi4]], [[5hi3]], [[5hhx]], [[5hhv]] - hIL-17A + peptide inhibitor + antibody<BR /> |
| **[[1jpy]] – hIL-17F<BR /> | | **[[1jpy]], [[6hgo]] – hIL-17F<BR /> |
| **[[3jvf]] - hIL-17F + IL-17 receptor α | | **[[6ppg]] – hIL-17F + antibody<BR /> |
| | **[[3jvf]], [[6hg4]], [[6hg9]] - hIL-17F + IL-17 receptor α |
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| *IL-18 (Interferon-γ inducing factor) | | *IL-18 (Interferon-γ inducing factor) |
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| *IL-36 | | *IL-36 |
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| | **[[6hpi]] - hIL-36 α - NMR<br /> |
| **[[4ize]] - hIL-36 γ<br /> | | **[[4ize]] - hIL-36 γ<br /> |
| **[[6p9e]] - hIL-36 g + antagonist<br /> | | **[[6p9e]] - hIL-36 γ + antagonist<br /> |
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| *IL-37 | | *IL-37 |
3D structures of interleukin
Updated on 26-August-2020
{"openlevels":0}
- IL-1 α
- 2ila - hIL-1 α - human
- 2kki - hIL-1 α residues 121-271
- 2l5x – hIL-1 α residues 121-271 + calcium-binding protein A13 – NMR
- IL-1 β
- 2nvh, 9ilb, 1iob, 5i1b, 2i1b, 4i1b, 1i1b - hIL-1 β
- 1tp0, 1t4q, 1too, 1twe, 1twm, 1s0l, 1l2h, 1hib, 21bi, 31bi, 41bi - hIL-1 β (mutant)
- 6i1b, 7i1b - hIL-1 β - NMR
- 3ltq - hIL-1 β residues 117-269
- 3pok - hIL-1 β residues 117-269 (mutant)
- 6y8i, 6y8m - hIL-1 β residues 117-269 + pyridine derivative
- 1itb - hIL-1 β + IL-1 receptor 1 extracellular domain
- 3o4o - hIL-1 β + IL-1 receptor 2 + IL-1 receptor accessory protein
- 4dep - hIL-1 β + IL-1 receptor 1 + IL-1 receptor accessory protein
- 4g6j, 4g6m, 5bvp - hIL-1 β + antibody
- 2kh2 - hIL-1 β + SCFV - NMR
- 1md6 – mIL-1F5 – mouse
- 2mib, 8i1b - mIL-1 β
- 2wry - cIL-1 β – chicken
- 3nj5, 4x3a, 4x39, 4x38, 4x37 – cIL-1 β (mutant)
- IL-2 (T-cell growth factor)
- 1m47, 1m4c, 3ink – hIL-2
- 3qb1 - hIL-2 (mutant)
- 1irl – hIL-2 (mutant) - NMR
- 5m5e - hIL-2 + IL-2 receptor β + cytokine receptor common γ
- 2erj, 2b5i - hIL-2 + IL-2 receptor α and β + cytokine receptor common γ
- 1z92 - hIL-2 + IL-2 receptor α
- 3qaz - hIL-2 + IL-2 receptor β and γ
- 1qvn, 1nbp, 1m4a, 1m4b – hIL-2 (mutant) + inhibitor
- 1pw6, 1py2, 1m48, 1m49 – hIL-2 + inhibitor
- 4nej, 4nem – hIL-2 + methylfuran carboxylate derivative
- 5lqb - hIL-2 + antibody
- 4yue - mIL-2 + antibody
- 4yqx - IL-2 + antibody - rat
- 4zf7 – hIL-2 - ferret
- IL-3
- 1jli – hIL-3 (mutant) – NMR
- 6nmy – hIL-3 + IL-3 receptor α + cytokine receptor common subunit β
- 5uv8, 5uwc – hIL-3 (mutant) + IL-3 receptor α
- 2l3o – mIL-3 residues 33-156 (mutant) - NMR
- IL-4
- 2b8u, 1hik, 2int, 1rcb – hIL-4
- 2cyk, 1cyl, 1itm, 1bbn, 1bcn, 1iti, 1itl – hIL-4 - NMR
- 2b8x, 2b8y, 2b8z, 2b90, 2b91, 2d48, 1hzi, 1hij - hIL-4 (mutant)
- 5fhx - hIL-4 + antibody
- 1iar - hIL-4 + IL-4 receptor α (mutant)
- 3bpl - hIL-4 + IL-4 receptor α + cytokine receptor common γ
- 6oel - hIL-4 + IL-4 receptor α + cytokine receptor common γ + antibody
- 3qb7 - hIL-4 + cytokine receptor common γ
- 4ydy – hIL-4 + darpin
- 3bpn - hIL-4 + IL-4 receptor α + IL-13 receptor α
- IL-5
- 1hul – hIL-5
- 3qt2 - hIL-5 + IL-5 receptor α (mutant)
- 3va2 - hIL-5 + IL-5 receptor α
- 3b5k – mIL-5
- IL-6
- 1alu – hIL-6
- 1il6, 2il6 – hIL-6 - NMR
- 1p9m - hIL-6 + IL-6 receptor α and β
- 5fuc - hIL-6 + IL-6 receptor α + VHH6
- 4j4l – hIL-6 + internalin B
- 4ni7, 4ni9 – hIL-6 + nucleotide aptamer
- 4cni, 4o9h, 4zs7 – hIL-6 + antibody
- 2l3y - mIL-6 residues 27-211 - NMR
- 1i16 – IL-6 + IL-6 receptor β - Herpesvirus 8
- IL-7
- 3di2, 3di3 - hIL-7 residues 26-177 + IL-7 receptor α ectodomain
- IL-8
- IL-10
- IL-10 viral
- 1vlk - hvIL-10 residues 26-170 - human herpesvirus 4
- 1y6m - hvIL-10 residues 26-170 + IL-10 receptor α
- 1y6n - hvIL-10 residues 26-170 (mutant) + IL-10 receptor α
- 1lqs - hvIL-10 residues 20-176 + IL-10 receptor α - human herpesvirus 5
- 1lk3 - hvIL-10 residues 26-175 + antibody
- IL-11
- IL-12
- 1f45 - hIL-12 α and β (mutant)
- 1f42 - hIL-12 β P40 domain
- 3hmx - hIL-12 α and β+ antibody
- 5mj3, 5mj4, 5njd - hIL-12 β + hIL-23 α + antibody
- 5mzv - hIL-12 β + hIL-23 α + hIL-23 receptor + antibody
- 5mxa - hIL-12 β + hIL- 23 α
- 5mj3, 5mj4 - hIL-12 β + hIL-23 α + alphabody MB3
- 3qwr - hIL-12 β + hIL- 23 α + adnectin
- 6uib - hIL-12 β + hIL- 23 α + peptide
- 6sff - mIL-12 β
- IL-13
- 1ijz, 1ik0 – hIL-13 – NMR
- 1ga3 - hIL-13 residues 21-132 - NMR
- 3l5w, 3l5x, 3g6d, 4i77, 4ps4 - hIL-13 residues 35-146 + antibody
- 3lb6 - hIL-13 + IL-13 receptor α2
- 3bpo, 5e4e - hIL-13 residues 20-145 + IL-4 receptor α + IL-13 receptor α
- 5l6y - hIL-13 + antibody
- IL-15
- 2xqb – hIL-15 + antibody
- 2psm, 2z3q, 2z3r - hIL-15 + IL-15 receptor α
- 4gs7 - hIL-15 + IL-15 receptor α + IL-2 receptor β,γ
- IL-16
- 1i16 – hIL-16 - NMR
- 1x6d – hIL-16 PDZ domain – NMR
- IL-17
- 4hr9 - hIL-17A (mutant)
- 5n92 - hIL-17A + hIL-17F
- 4hsa - hIL-17A (mutant) + IL-17A receptor α
- 5nan - hIL-17A + hIL-17F + IL-17A receptor α
- 2vxs, 4qhu - hIL-17A + antibody
- 5vb9 - hIL-17A + peptide inhibitor
- 5hi5, 5hi4, 5hi3, 5hhx, 5hhv - hIL-17A + peptide inhibitor + antibody
- 1jpy, 6hgo – hIL-17F
- 6ppg – hIL-17F + antibody
- 3jvf, 6hg4, 6hg9 - hIL-17F + IL-17 receptor α
- IL-18 (Interferon-γ inducing factor)
- 3wo2 – hIL-18
- 4xfu, 4xft, 4xfs - hIL-18 (mutant)
- 1j0s – hIL-18 - NMR
- 4hjj - hIL-18 + antibody
- 2vxt - hIL-18 (mutant) + antibody
- 3f62 - hIL-18 residues 37-193 (mutant) + IL-18 binding protein
- 4eee, 4ekx - hIL-18 (mutant) + 14L protein
- 3wo3, 4r6u - hIL-18 + IL-18 receptor
- 3wo4 - hIL-18 + IL-18 receptor + IL-18 receptor accessory protein
- IL-19
- IL-20
- 4doh - hIL-20 + IL-20 receptor α,β
- IL-21
- 2oqp– hIL-21 – NMR
- 3tgx - hIL-21 + IL-21 receptor α (mutant)
- IL-22
- 1ykb, 1m4r – hIL-22
- 3g9v - hIL-22 residues 29-179 + IL-22 receptor α2
- 3dlq, 3dgc - hIL-22 residues 29-179 (mutant) + IL-22 receptor α1
- 3q1s - hIL-22 residues 29-179 (mutant) + antibody
- 4o6k – IL-22 – zebra fish
- IL-23
- 3d87 - hIL-23 α
- 3d85 - hIL-23 α + antibody
- 4grw - hIL-23 α + + hIL-12 β + nanobody
- 3duh - hIL-23 α + hIL-12 β
- IL-24
- 6gg1 - hIL-24
- 6df3 - hIL-24 + IL—22 receptor α1 + IL-20 receptor β
- IL-28
- 3hhc – hIL-28B
- 5t5w - hIL-28B + IL—10 receptor β + IL-28 receptor α
- IL-29
- IL-33
- 2kll - hIL-33 residues 110-270 - NMR
- IL-34
- 4dkc - hIL-34
- 4dkd - hIL-34 active core + macrophage colony-stimulating factor 1 receptor
- 4dke, 4dkf - hIL-34 active core + antibody
- 4exn - mIL-34
- 4exp - mIL-34 active core + macrophage colony-stimulating factor 1 receptor
- IL-36
- 6hpi - hIL-36 α - NMR
- 4ize - hIL-36 γ
- 6p9e - hIL-36 γ + antagonist
- IL-37
