Furin: Difference between revisions

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== Relevance ==
== Relevance ==


High furin activity promotes the malignant phenotype of cancer cells in head and neck squamous cell carcinoma, breast cancer and <ref>PMID:28369813</ref>.  Furin has a role in atherosclerosis<ref>PMID:28400053</ref>.  The new coronavirus SARS-CoV19 genome sequence shows a furin-like cleavage site in the spike protein.  This cleavage site has potential implications in the development of antivirals<ref>PMID:32057769</ref>.
High furin activity promotes the malignant phenotype of cancer cells in head and neck squamous cell carcinoma, breast cancer and <ref>PMID:28369813</ref>.  Furin has a role in atherosclerosis<ref>PMID:28400053</ref>.  The new coronavirus SARS-CoV19 genome sequence shows a furin-like cleavage site in the spike protein.  This cleavage site has potential implications in the development of antivirals<ref>PMID:32057769</ref>. See [[SARS-CoV-2 protein S priming by furin]], an animation.


== Structural highlights ==
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