CREB-binding protein 3D structures

Updated on 27-October-2020 - For a general description of the protein see CREB-binding_protein

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• CBP domains – BZIP 283-341; zinc finger 376-400; KIX 587-673; bromodomain 1081-1197; catalytic core 1073-1550; ZZ 1699-1751; TAZ2 1763-1854; IBiD 2067-2112; nuclear coactivator binding 2059-2441
  • 1wo3, 1wo4, 1wo5, 1wo6, 1wo7 – hCBP zinc finger domain (mutant) – human - NMR
    
  • 2d82 – hCBP bromodomain - NMR
    
  • 3dwy, 4ouf, 4whu – hCBP bromodomain
    
  • 3p1c, 3p1d, 3p1e, 3p1f, 3svh, 4a9k, 4tqn, 4ts8, 4yk0, 5cgp, 5dbm, 5eic, 5eng, 5ep7, 5h85, 5i83, 5i86, 5i89, 5i8b, 5i8g, 5j0d, 5ktu, 5ktw, 5ktx, 5tb6 – hCBP bromodomain + inhibitor
    
  • 2l84, 2l85 – hCBP bromodomain + inhibitor - NMR
    **4i9o – mCBP GACKIX domain (mutant) - mouse
    
  • 1f81 – mCBP TAZ2 domain - NMR
    
  • 1u2n – mCBP TAZ1 domain - NMR
    
  • 1jjs – mCBP IBiD domain - NMR
    
  • 1liq – mCBP CH1 domain - NMR
    
  • 1tot – mCBP ZZ domain – NMR
    
  • 2kkj – mCBP nuclear coactivator binding domain - NMR
    
  • 6u7g – mCBP catalytic core
    
• CBP complex with small molecule
  • 5lpj, 5lpl, 5nlk, 5nrw, 5nu3, 5mqe, 5mqg, 5mqk, 5mme, 5mmg, 5mpk, 5mpn, 5mpz, 5owk, 5w0e, 5w0f, 5w0i, 5w0l, 5w0q, 6alb, 6alc, 6axq, 6ay3, 6ay5, 6fqo, 6fqt, 6fqu, 6frf, 6qst, 6yij, 6yik, 6yil, 6yim – hCBP bromodomain + inhibitor
    
  • 5xxh, 6dmk – hCBP bromodomain + cancer drug
    
• CBP complex with protein
  • 1zoq – hCBP + interferon regulatory factor 3
    
  • 2n1a – hCBP + small ubiquitin-related modifier - NMR
    
  • 5jem – hCBP IBiD domain + interferon-3
    
  • 6es7 – hCBP IBiD domain + nuclear receptor coactivator - NMR
    
  • 2kje – hCBP TAZ2 domain + adenoviral E1A peptide - NMR
    
  • 1jsp – hCBP bromodomain + p53 peptide - NMR
    
  • 2kwf – hCBP KIX domain + transcription factor 4 – NMR
    
  • 6svh – hCBP KIX domain + MLL/C-Myb
    
  • 2lxs, 2lxt – hCBP KIX domain + histone methyltransferase MLL peptide – NMR
    
  • 2rny – hCBP bromodomain + histone H3 peptide - NMR
    
  • 4n3w, 4n4f - hCBP bromodomain + histone H4 peptide
    
  • 4nr4, 4nr5, 4nr6, 4nr7, 4nyv, 4nyw, 4nyx- hCBP bromodomain + ligand
    
  • 5zko – hCBP BZIP domain + CREB-regulated transcription coactivator + DNA
    
  • 5zk1 – hCBP BZIP domain (mutant) + CREB-regulated transcription coactivator + DNA
    
  • 1kbh – mCBP IBiD domain + nuclear receptor coactivator - NMR
    
  • 2c52 – mCBP IBiD domain + nuclear receptor coactivator - NMR
    
  • 1r8u – mCBP TAZ1 domain + P300-interacting transactivator - NMR
    
  • 1l8c – mCBP TAZ1 domain + hypoxia-inducible factor 1α - NMR
    
  • 2lww - mCBP TAZ1 domain + nuclear transcription factor RELA – NMR
    
  • 2ka6 – mCBP TAZ2 domain + STAT1-TAD - NMR
    
  • 2ka4 – mCBP TAZ2 domain + STAT2-TAD - NMR
    
  • 1kdx – mCBP KIX domain + CREB kinase inducible domain - NMR
    
  • 2l14 – mCBP nuclear coactivator binding domain + p53 peptide - NMR
    
  • 1sb0 – mCBP KIX domain + protein c-Myb – NMR
    
  • 2agh – mCBP KIX domain + protein c-Myb + zinc finger protein HRX – NMR
    
  • 2lqh, 2lqi – mCBP KIX domain + forkhead box O3 – NMR
    
  • 5u4k – hCBP KIX domain + p65 transactivation domain – NMR
    
  • 6dnq – mCBP KIX domain + BZIP factor + C-Myb
    
  • 6dmx – mCBP BZIP domain + BZIP factor + C-Myb
    

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Michal Harel, Jaime Prilusky