6l99: Difference between revisions

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<StructureSection load='6l99' size='340' side='right'caption='[[6l99]]' scene=''>
<StructureSection load='6l99' size='340' side='right'caption='[[6l99]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L99 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6L99 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6l99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L99 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6l99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l99 OCA], [http://pdbe.org/6l99 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6l99 RCSB], [http://www.ebi.ac.uk/pdbsum/6l99 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6l99 ProSAT]</span></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l99 OCA], [https://pdbe.org/6l99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l99 RCSB], [https://www.ebi.ac.uk/pdbsum/6l99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l99 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/R144A_HUMAN R144A_HUMAN] E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.<ref>PMID:24979766</ref>
==See Also==
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Miyamoto K]]
[[Category: Miyamoto K]]