6l99
From Proteopedia
Jump to navigationJump to search
Zinc finger of RING finger protein 144A
| ||||||||||||
Structural highlights
FunctionR144A_HUMAN E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.[1] See AlsoReferences
| ||||||||||||||||||
This page was last modified 10:54, 14 June 2023.