LRRK2 3D structures: Difference between revisions

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Michal Harel (talk | contribs)
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New page: ==3D structures of LRRK2== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} Domains: GTPase 1329-1520; WD40 2142-2527; C-terminal 1330-2527 7li4 – hLR...
 
Michal Harel (talk | contribs)
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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Domains: GTPase 1329-1520; WD40 2142-2527; C-terminal 1330-2527
*LRRK2


**[[6xr4]] – hLRRK2 – human - Cryo EM<br />
**[[7li4]] – hLRRK2 + ATP + GDP <br />
**[[7lht]], [[7lhw]] – hLRRK2 + ATP + GDP – Cryo EM<br />
**[[7li3]] – hLRRK2 (mutant) + ATP + GDP <br />
**[[9ci3]] – hLRRK2 (mutant) + 14-3-3 protein gamma + GDP – Cryo EM<br />
**[[8tzh]] – hLRRK2 (mutant) + darpin + GDP – Cryo EM<br />
**[[8vh4]], [[8vh5]] – hLRRK2 + Rab12 + GDP + GNP – Cryo EM<br />
**[[8fo2]], [[8fo8]], [[8fo9]] – hLRRK2 + Rab29 + GDP + ATP – Cryo EM<br />
**[[8u8a]], [[8u8b]] – hLRRK2 + GDP + drug – Cryo EM<br />
**[[8u7l]] – hLRRK2 + GDP + inhibitor – Cryo EM<br />
**[[9cho]] – hLRRK2 543-2527 + GDP + inhibitor – Cryo EM<br />
**[[8tzf]] – hLRRK2 + ankyrin repeat protein + GDP + inhibitor – Cryo EM<br />


[[7li4]] – hLRRK2 + ATP + GDP – human<br />
*LRRK2 GTPase domain 1329-1520
[[6xr4]] – hLRRK2 – Cryo EM<br />
 
[[7lht]], [[7lhw]] – hLRRK2 + ATP + GDP – Cryo EM<br />
**[[2zej]], [[3d6t]] – hLRRK2 GTPase domain + GDP <br />
[[7li3]] – hLRRK2 (mutant) + ATP + GDP <br />
**[[6oje]], [[6ojf]], [[6xaf]] – hLRRK2 GTPase domain (mutant) + GDP <br />
[[2zej]], [[3d6t]] – hLRRK2 GTPase domain + GDP <br />
 
[[6oje]], [[6ojf]], [[6xaf]] – hLRRK2 GTPase domain (mutant) + GDP <br />
*LRRK2 Roc domain
[[6vp7]], [[6vp8]] – hLRRK2 C-terminal – Cryo EM<br />
 
[[6vno]], [[6vp6]] – hLRRK2 C-terminal + GDP – Cryo EM<br />
**[[9c76]] – hLRRK2 + GDP + drug <br />
[[6dlo]], [[6dlp]] – hLRRK2 WD40 domain <br />
 
*LRRK2 WD40 domain 2142-2527
 
**[[6dlo]], [[6dlp]] – hLRRK2 WD40 domain <br />
**[[9c61]] – hLRRK2 WD40 domain + inhibitor<br />
 
*LRRK2 C-terminal domain 1330-2527
 
**[[6vp7]], [[6vp8]] – hLRRK2 C-terminal – Cryo EM<br />
**[[6vno]], [[6vp6]] – hLRRK2 C-terminal + GDP – Cryo EM<br />
**[[8tzb]], [[8tzc]], [[8tze]], [[8tzg]] – hLRRK2 C-terminal + inhibitor – Cryo EM<br />
**[[8fo7]], [[8smc]], [[8txz]], [[8u7h]] – hLRRK2 C-terminal + GDP + inhibitor – Cryo EM<br />
**[[8u1b]] – hLRRK2 C-terminal + darpin <br />
**[[9dmi]] – hLRRK2 C-terminal + darpin + inhibitor – Cryo EM<br />
**[[8tyq]] – hLRRK2 C-terminal (mutant) + ankyrin repeat protein + inhibitor – Cryo EM<br />
 
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[[Category:Topic Page]]
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