2w1b: Difference between revisions

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<StructureSection load='2w1b' size='340' side='right'caption='[[2w1b]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
<StructureSection load='2w1b' size='340' side='right'caption='[[2w1b]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W1B FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W1B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1oy8|1oy8]], [[1t9u|1t9u]], [[1iwg|1iwg]], [[1t9t|1t9t]], [[1t9y|1t9y]], [[1t9w|1t9w]], [[2j8s|2j8s]], [[1oy6|1oy6]], [[1t9x|1t9x]], [[2gif|2gif]], [[2hrt|2hrt]], [[1oye|1oye]], [[1oyd|1oyd]], [[1oy9|1oy9]], [[1t9v|1t9v]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1b OCA], [https://pdbe.org/2w1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w1b RCSB], [https://www.ebi.ac.uk/pdbsum/2w1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1b OCA], [https://pdbe.org/2w1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w1b RCSB], [https://www.ebi.ac.uk/pdbsum/2w1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Beis, K]]
[[Category: Beis K]]
[[Category: Drew, D]]
[[Category: De Gier JW]]
[[Category: Flaig, R]]
[[Category: Drew D]]
[[Category: Gier, J W.De]]
[[Category: Flaig R]]
[[Category: Iwata, S]]
[[Category: Iwata S]]
[[Category: Klepsch, M M]]
[[Category: Klepsch MM]]
[[Category: Newstead, S]]
[[Category: Newstead S]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Multidrug efflux]]
[[Category: Transport]]
[[Category: Transporter]]