7x3k: Difference between revisions
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== | ==Cryo-EM structure of RAC in the State C2 RNC-RAC complex== | ||
<StructureSection load='7x3k' size='340' side='right'caption='[[7x3k]]' scene=''> | <StructureSection load='7x3k' size='340' side='right'caption='[[7x3k]], [[Resolution|resolution]] 6.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X3K FirstGlance]. <br> | <table><tr><td colspan='2'>[[7x3k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X3K FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x3k OCA], [https://pdbe.org/7x3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x3k RCSB], [https://www.ebi.ac.uk/pdbsum/7x3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x3k ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x3k OCA], [https://pdbe.org/7x3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x3k RCSB], [https://www.ebi.ac.uk/pdbsum/7x3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x3k ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SSZ1_YEAST SSZ1_YEAST] Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain. SSZ1 is required for ZUO1 to function efficiently as a J-protein for SSB1/SSB2. Also involved in pleiotropic drug resistance by post-translational activation of transcription factor PDR1.<ref>PMID:11929993</ref> <ref>PMID:15456889</ref> <ref>PMID:15908962</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: N | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Chen Y]] | |||
[[Category: Gao N]] | |||
Latest revision as of 06:42, 25 June 2025
Cryo-EM structure of RAC in the State C2 RNC-RAC complex
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