4lxa: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lxa]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LXA FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lxa]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LXA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YS:(1R,3S,4S,5R)-3-{4-AMINO-3-FLUORO-5-[(1,1,1,3,3,3-HEXAFLUOROPROPAN-2-YL)OXY]BENZYL}-5-[(3-TERT-BUTYLBENZYL)AMINO]TETRAHYDRO-2H-THIOPYRAN-4-OL+1-OXIDE'>1YS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YS:(1R,3S,4S,5R)-3-{4-AMINO-3-FLUORO-5-[(1,1,1,3,3,3-HEXAFLUOROPROPAN-2-YL)OXY]BENZYL}-5-[(3-TERT-BUTYLBENZYL)AMINO]TETRAHYDRO-2H-THIOPYRAN-4-OL+1-OXIDE'>1YS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxa OCA], [https://pdbe.org/4lxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lxa RCSB], [https://www.ebi.ac.uk/pdbsum/4lxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lxa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxa OCA], [https://pdbe.org/4lxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lxa RCSB], [https://www.ebi.ac.uk/pdbsum/4lxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lxa ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 06:41, 17 October 2024

Crystal Structure of Human Beta Secretase in Complex with Compound 11a

4lxa, resolution 1.95Å

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