DNA Repair: Difference between revisions
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'''DNA Repair''' is necessary to maintain genome fidelity. Errors in DNA can arise from many different sources. Errors introduced in the replication process are the simplest source. This leads to non-Watson-Crick base pairs and local distortions in the helix. Bases can also be damaged by oxidizing agents, alkylating agents or UV light. This page will discuss different strategies for repairing these types of DNA damage. Click the green links to see depictions that match the words. | '''DNA Repair''' is necessary to maintain genome fidelity. Errors in DNA can arise from many different sources. Errors introduced in the replication process are the simplest source. This leads to non-Watson-Crick base pairs and local distortions in the helix. Bases can also be damaged by oxidizing agents, alkylating agents or UV light. This page will discuss different strategies for repairing these types of DNA damage. Click the green links to see depictions that match the words. | ||
<StructureSection load=' | <StructureSection load='2aor' size='350' side='right' scene='' caption='MutH complex with DNA, AMP derivative and Ca+2 ion (PDB id [[2aor]])'> | ||
==DNA Mismatch Repair by MutH== | ==DNA Mismatch Repair by MutH== | ||
