8i40: Difference between revisions
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==Crystal structure of ASCT from Trypanosoma brucei in complex with CoA.== | |||
<StructureSection load='8i40' size='340' side='right'caption='[[8i40]], [[Resolution|resolution]] 2.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8i40]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I40 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.79Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i40 OCA], [https://pdbe.org/8i40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i40 RCSB], [https://www.ebi.ac.uk/pdbsum/8i40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i40 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/Q386P1_TRYB2 Q386P1_TRYB2] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.[PIRNR:PIRNR000858] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Trypanosoma brucei brucei TREU927]] | ||
[[Category: | [[Category: Balogun EO]] | ||
[[Category: | [[Category: Boshart M]] | ||
[[Category: | [[Category: Bringaud F]] | ||
[[Category: | [[Category: Fukuda K]] | ||
[[Category: | [[Category: Harada S]] | ||
[[Category: Mochizuki | [[Category: Hirayama K]] | ||
[[Category: | [[Category: Inaoka DK]] | ||
[[Category: Iyoda K]] | |||
[[Category: Kita K]] | |||
[[Category: Kurasawa H]] | |||
[[Category: Mazet M]] | |||
[[Category: Millerioux Y]] | |||
[[Category: Mochizuki K]] | |||
[[Category: Nakai U]] | |||
[[Category: Shiba T]] | |||
Latest revision as of 11:42, 1 February 2024
Crystal structure of ASCT from Trypanosoma brucei in complex with CoA.
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