Gp41 3D Structures

3D Structures of Gp41

Updated on 01-July-2024

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• Gp41 from HIV-1; Domains – helix-bundle – 1-40; ectodomain – 93-165;core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854
  • 2zfc, 3u91 – Gp41 N-terminal residues 1-49
    
  • 3k9a – Gp41 residues 1-108 (mutant)
    
  • 1aik, 1df4, 1df5, 1qr8, 1qr9, 1dlb, 1jpx, 1szt, 3vu5, 3vu6 - Gp41 N-peptide domain
    
  • 1env, 3cp1, 3cyo, 1f23, 1k33, 1k34, 1i5x, 1i5y, 2ot5, 5ka6, 5ka5, 4i2l – Gp41 N-peptide domain (mutant)
    
  • 5jyn, 6b3u, 6dln, 7loi – Gp41 transmembrane domain - NMR
    
  • 2mk3 – Gp41 ectodomain - NMR
    
  • 5vwl – Gp41 tail domain - NMR
    
  • 6uju, 6ujv, 7loh – Gp41 transmembrane+tail domains (mutant) - NMR
    
  • 3f4y, 3f4z, 3f50 – Gp41 + Gp120 six-helix bundle
    
• Gp41 complexes
  • 6v0r, 6vfl, 6vl5, 6vrw, 7l6o, 7l7t, 7l7u, 7sc5, 7ska – Gp41 core + Gp120 – Cryo EM
    
  • 5v8l, 5v8m, 5uty, 5utf, 5um8, 5jsa, 5js9, 5i8h, 5d9q, 5cjx, 5c7k, 6ck9, 6chb, 6ch9, 6ch8, 6ch7, 5w6d, 4nrx, 5fyk, 5fyj, 4nco, 6mdt, 6mco, 6vkn, 6wix – Gp41 core + Gp120 + antibody
    
  • 7l6o – Gp41 core + Gp120 Clade A/E (mutant)
    
  • 3j5m, 6mpg, 6mph, 6n1v, 6n1w, 6nfc, 6x96, 6x97, 7kde, 7lg6, 7lu9, 7lxm, 7lxn, 7ly9, 7mdt, 7mdu, 7mxe, 7pc2, 7rsn, 7rso, 7sd3, 7sq1, 7t73, 7t74, 7t75, 7t76, 7t77,7tfn, 7tfo, 7ugn, 7ugp, 7ugq, 7zlk, 7z3a, 8fis – Gp41 core + Gp120 Clade A/E + antibody – Cryo EM
    
  • 6ot1, 6x98, 7n28 – Gp41 (mutant) + Gp120 Clade A/E (mutant) + antibody – Cryo EM
    
  • 6nnj, 6nnf, 6nm6 – Gp41 core (mutant) + Gp120 + antibody
    
  • 6opa, 6vzi, 6w03 – Gp41 core + Gp160 + antibody
    
  • 6oz4, 6ozc, 6vn0, 7ugo – Gp41 core + Gp160 + antibody – Cryo EM
    
  • 7lpn – Gp41 core + Gp160 + VHH – Cryo EM
    
  • 4cc8, 6cdi, 6orn, 6oo, 6orp, 6orq, 6okp, 6nqd, 6mn7, 6cuf, 6cue, 6olp, 6pw6, 6u59, 6uda, 6udk, 6ulc, 6um6, 6um7, 6v8x, 6v8z, 6vlr, 6vo0, 6vo1, 6vtt, 6vy2, 6nf5, 6nf2, 6nfc, 6oro, 6osy, 6u59, 6vi0, 6vo3, 6x9r, 6x9s, 6x9t, 6x9u, 6x9v, 6xrt, 7l86, 7l87, 7l88, 7l89, 7l8a, 7l8b, 7l8c, 7l8d, 7l8s, 7l8t, 7l8u, 7l8w, 7l8x, 7l8y, 7l8z, 7l90, 7ll1, 7ll2, 7llk, 7lo6, 7lua, 7mxd, 7n65, 7pc2, 7rai, 7t74, 7t76, 7ucg – Gp41 core + Gp120 + antibody – Cryo EM
    
  • 4tvp, 6utk, 6v6w, 7kmd, 7ucf – Gp41 core + Gp120 + antibody
    
  • 6nc3, 6nc2 – Gp41 core (mutant) + Gp120 + antibody – Cryo EM
    
  • 5u1f, 5thr – Gp41 core + Gp120 + antibody + CD4
    
  • 6u0l, 6u0n, 6x5b, 8dc5 – Gp41 core + Gp120 + antibody + CD4 – Cryo EM
    
  • 6opn, 6x5c – Gp41 core + Gp160 + CD4 – Cryo EM
    
  • 6opo, 6opp, 6opq, 6u0l – Gp41 core + Gp160 + antibody + CD4 – Cryo EM
    
  • 7txd – Gp41 core + Gp120 + darpin + CD4 – Cryo EM
    
  • 6um5 – Gp41 core + Gp120 + antibody + CH848 – Cryo EM
    
  • 6vpx, 7lok – Gp41 core + Gp120 + antibody + peptide – Cryo EM
    
  • 2z2t, 2zzo, 3aha, 3vie, 2r3c, 2r5b, 2r5d, 3l36, 3l37, 3vgy, 3vh7, 3vtp, 5h0n, 5zpw – Gp41 N-peptide domain + fusion inhibitor peptide
    
  • 5hm1 – Gp41 core + llama antibody
    
  • 3p30 – Gp41 ectodomain + antibody
    
  • 3o3x – arGp41 - artificial
    
  • 4dzu – arGp41 + 3-α
    
  • 4dzv – arGp41 + 4-α/β
    
• Gp41 from SIV (Simian Immunodeficiency Virus)
  • 2siv – Gp41 core
    
  • 2ezo, 2ezp, 2ezq, 2ezr, 2ezs, 1qce – Gp41 core - NMR
    
  • 1qbz, 1jq0 – Gp41 core (mutant)
    
  • 7t2p, 7t4g, 8dua – Gp41 core + Gp120 + antibody – Cryo EM
    

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Michal Harel, Openfox