Kinesin 3D Structures

3D Structures of Kinesin

Updated on 13-June-2023

{"openlevels":0}

• KIF1A, KIF1B, KIF1C or kinesin-3
  • 4ejq, 4egx - hKIF1A CC1-FHA domain 430-607 - human
    
  • 1bg2 – hKIF MD
    
  • 5lt3, 5lt4, 5lt2, 5lt0, 5lt1 – hKIF1 MD (mutant)
    
  • 2g1l - hKIF1C FHA domain
    
  • 5wdh – hKIF1C MD
    
  • 2eh0 - hKIF1B FHA domain – NMR
    
  • 4hna, 4lnu – hKIF1 + Tubulin + designed ankyrin repeat protein + Mg-ADP + GDP + GTP + AlF4
    
  • 4uxy – hKIF1 MD + Tubulin + GDP + GTP – Cryo EM
    
  • 6ojq – hKIF1 MD + Tubulin + G2P + GTP – Cryo EM
    
  • 4uy0 – hKIF1 MD + Tubulin + GDP + GTP + ADP – Cryo EM
    
  • 4uxo, 4uxp, 4uxr, 4uxs, 4uxt - hKIF + tubulin 1B, 2B chains + GDP + GTP – Cryo EM
    
  • 2p4n – hKIF+ Tubulin – EM docking
    
  • 1mkj – hKIF MD+docked FNL
    
  • 6zph – hKIF MD + KIF-binding protein – Cryo EM
    
  • 2wbe – bKIF MD+FNL+Tubulin +AMPPNP – bovine
    
  • 3edl – bKIF MD+ Tubulin – EM
    
  • 3uyq – pKIF1A head+AMPPNP – pig
    
  • 2hxh - pKIF1A head+ADP
    
  • 2hxf - pKIF1A head+AMPPNP
    
  • 1ia0 – pKIF1A MD+Tubulin +ATP
    
  • 2zfi, 2zfj, 2zfk, 2zfl, 2zfm – mKIF1A – mouse
    
  • 1vfv, 1vfw – mKIF1A MD+Mg-AMPPNP
    
  • 1vfx - mKIF1A MD+ADP-Mg-AlFx
    
  • 7eo9, 7eob - mKIF1A MD (mutant) +ADP-Mg-AlFx
    
  • 1vfz - mKIF1A MD+ADP-Mg-VO4
    
  • 4atx - rKIF MD+ Tubulin – rat - Cryo EM
    
  • 2owm – NcKIF1C MD – Neurospora crassa
    
• KIF2A, KIF2B, KIF2C or kinesin-13
  • 2heh, 4ubf, 5y05 – hKIF2C
    
  • 2gry – hKIF2+ADP
    
  • 6bbn – hKIF2A MD + Tubulin + Darpin
    
  • 5mio – hKIF2C MD + Tubulin
    
  • 1v8j, 5xja, 5xjb – mKIF2C MD+Mg-ADP
    
  • 1i5s - mKIF2C MD (mutant)+Mg-ADP
    
  • 1i6i - mKIF2C MD (mutant)+Mg-AMPPCP
    
  • 1v8k - mKIF2C MD+Mg-AMPPNP
    
  • 2vvg – KIF2 MD – Giardia intestinalis
    
• KIF3A, KIF3B, KIF3C or kinesin-2
  • 3b6u, 3b6v – hKIF3B MD
    
  • 5wde – hKIFC3+ADP
    
• KIF4A, KIF4B or kinesin-4
  • 3zfc, 3zfd – mKIF4 MD+Mg-AMPPNP
    
• KIF5B, KIF5C or kinesin-1
  • 6ign, 6igv – mKIF5B coiled coil domain 444-566
    
  • 3wrd – mKIF5C
    
  • 3x2t – mKIF5C + ADP
    
  • 3j6h – mKIF5C MD+Mg-GTP + G2P + tubulin
    
  • 3j8x, 3j8y – mKIF5C MD+ GTP + GDP + tubulin
    
• KIF7 or kinesin-4
  • 4a14 – hKIF7 MD
    
  • 2xt3 – hKIF7 MD (mutant)
    
  • 6mlr – hKIF7 MD + Tubulin + GTP + GDP + ANP – Cryo EM
    
  • 6mlq – hKIF7 MD + Tubulin + GTP + GDP + ADP – Cryo EM
    
  • 7rx0 – hKIF7 MD + GLI2 ANTubulin + GTP + GDP + G2P – Cryo EM
    
• KIF9 or kinesin-9
  • 3nwn – hKIF9+ADP
    
• KIF10A or kinesin-6
  • 3j2u – hKIF10A head domain – Cryo EM
    
  • 6b0c, 6b0l – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM
    
  • 6vpp – DmKlp61F + tubulin + GTP + GDP + Mg – Cryo EM
    
  • 6vpo – DmKlp61F + tubulin + GTP + GDP + ANP + Mg – Cryo EM
    
  • 6b0i – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM
    
• KIF11 or kinesin-5 or Eg5
  • 4b7b - hKIF11 (mutant) + ADP + Co + Cd
    
  • 3ken, 2wog, 2x2r, 2xae, 4bbg - hKIF11 +S-trityl-L-cysteine derivative + ADP + Mg
    
  • 3wpn - hKIF11 +inhibitor
    
  • 2uyi, 2uym, 2gm1, 2pg2, 2fme, 2x7d, 2x7c, 2ieh, 3cjo, 2g1q, 2fl2, 2fl6, 1yrs, 2q2y, 2fky, 2q2z, 3k3b, 2x7e, 4a50, 4a51, 3zcw, 6g6y, 6g6z, 6hkx, 6hky - hKIF11+inhibitor +ADP + Mg
    
  • 4bxn, 4as7 - hKIF11+inhibitor +ADP + Cd
    
  • 3l9h - hKIF11+inhibitor +ADP
    
  • 4zhi – hKIF11 MD +ADP
    
  • 1x88, 1q0b - hKIF11 +Mg + ADP+monastrol
    
  • 4ap0, 4a5y - hKIF11 +MgADP + ispinesib + Mg
    
  • 3hqd - hKIF11 +AMPPNP+Mg
    
  • 1ii6, 4a1z, 4a28 - hKIF11 +ADP+Mg
    
  • 4zca, 6tle, 6trl, 6y1i - hKIF11 (mutant) +ADP+Mg
    
  • 3k5e - hKIF11 +ADP+enastrol + Mg
    
  • 6zpi – hKIF11 MD + tubulin + GDP + GTP + Mg – Cryo EM
    
  • 4aqv, 4aqw – hKIF11 (mutant) + tubulin + GDP + GTP + Mg – Cryo EM
    
  • 4ck5, 4ck6, 4ck7 – hKIF11 (mutant) + tubulin + ADP + GDP + GTP + Mg – Cryo EM
    
  • 6ta3, 6tiw – hKIF11 MD (mutant) + tubulin + G2P + quinolin derivative + Mg – Cryo EM
    
  • 6ta4 – hKIF11 MD + tubulin + G2P + ANP + Mg – Cryo EM
    
  • 5m5i, 5m5l, 5m5m, 5m5n, 5m5o – KIF MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM
    
  • 6s8m – fyKIFCut7 MD + tubulin + GDP + GTP + ANP – Cryo EM
    
  • 5mm4, 5mm7 – UmKIF + tubulin + GDP + GTP + ANP + taxol – Ustilago maydis – Cryo EM
    
  • 7nb8 – PfKIF MD + tubulin + GTP + G2P – Plasmodium falciparum – Cryo EM
    
  • 7nba – PfKIF MD + tubulin + GTP + G2P + ANP – Cryo EM
    
• KIF13A, KIF13B or kinesin-3
  • 2cow – hKIF13B CAP-gly domain – NMR
    
  • 3gbj – hKIF13B MD+ADP
    
  • 2cjo – hKIF13+inhibitor 30
    
  • 3fm8 – hKIF13B FHA domain + centaurin-alpha-1
    
  • 3md8 – hKIF13B FHA domain + centaurin-alpha-1 + IP4
    
  • 5djo – mKIF13A CC1-FHA domain
    
  • 5djn – mKIF13A coiled-coil domain (mutant)
    
  • 5b64 – mKIF13B + MAGUK
    
  • 3kin, 2kin – rKIF MD
    
  • 6a1z – rKIF13B
    
  • 5zbs, 6a20, 7d8v – rKIF13B (mutant)
    
  • 7d8v – rKIF13B (mutant) + ADP
    
  • 5zbr – rKIF13B + AMPPNP
    
• KIF14 or kinesin-3
  • 6wwe, 6wwi, 6wwt – hKIF14 MD + Tubulin + GTP + GDP – Cryo EM
    
  • 6wwf, 6wwh, 6wwg, 6wwj, 6wwk, 6wwl, 6wwm, 6wwn, 6wwo, 6wwp, 6wwq, 6wwr, 6wws, 6wwu, 6wwv, 7lvq, 7lvr – mKIF14 MD + Tubulin + nucleotides – Cryo EM
    
  • 1f9t, 1f9u, 1f9v, 1f9w, 3kar - yKar3 MD (mutant) – yeast
    
  • 4etp - yKar3 MD (mutant) + VIK1
    
• KIF15 or kinesin-12
  • 4bn2 – hKIF15 MD
    
  • 7ryp – hKIF15 MD + KIF-binding protein – Cryo EM
    
• KIF16B or kinesin-3
  • 2v14 – hKIF16B
    
  • 6ee0 – hKIF16B PX domain 1026-1156
    
• KIF18A, KIF18B or kinesin-8
  • 3lre - hKIF18A MD
    
  • 5oam - hKIF18A MD + tubulin + GTP
    
  • 5ocu - hKIF18A MD + tubulin + GTP + GDP + ANP
    
  • 5ogc - hKIF18A MD + tubulin + GTP + GDP + taxol
    
  • 7rsi – hKIF18A MD + KIF-binding protein + ADP – Cryo EM
    
• KIF19A or kinesin-8
  • 5gsy – mKIF19A MD + GDP
    
  • 5gsz – mKIF19A MD + ADP
    
• KIF20A, KIF20B or kinesin-6
  • 6yip – hKIF20A coiled coil domain 596-668
    
  • 5nd3 – mKIF20A MD + tubulin
    
  • 5nd2, 5nd4 – mKIF20A MD + tubulin + ADP
    
  • 5nd7 – mKIF20A MD + tubulin + AMPPNP
    
  • 5lef – mKIF20A residues 603-665 + RAB-6
    
  • 5x3e - KLP MD - Caenorhabditis elegans
    
• KIF21A, KIF21B or kinesin-4
  • 5d3a – hKIF21A coiled coil domain 938-1017
    
  • 7klj – hKIF21A WD-repeat domain 1324-1640
    
• KIF22 or kinesin-10
  • 2edu – hKIF22 C-terminal – NMR
    
  • 6nje – hKIF22 MD +ADP
    
• KIF23 or kinesin-6
  • 3vhx – hKIF23 794-911 + ADP-ribosylation factor 6
    
  • 2ncd, 1cz7 – DmKIF MD non-claret disjuctional (NCD) dimer – Drosophila melanogaster
    
  • 2y5w, 2y65 - DmKIF MD
    
  • 4pxt, 4pxu – DmKIF MD (mutant)
    
  • 1n6m – DmKIF MD+FNL
    
  • 3l1c – DmNCD (mutant)
    
  • 1ry6 – PfKIF MD
    
  • 7nba – PfKlF + tubulin + GTP + G2P + ANP + Mg – Cryo EM
    
  • 7nb8 – PfKlF + tubulin + GTP + G2P + Mg – Cryo EM
    
  • 1goj – NcKIF MD
    
• Kinesin light chain (KLC)
  • 5oj8, 7ai4, 7aie – hKLC1 TPR domain
    
  • 6fuz – hKLC1 TPR domain + nanobody
    
  • 3edt – hKLC2
    
  • 3ceq, 3nf1 – hKLC2 TPR domain
    
  • 6f9i – hKLC2 + clcytenin peptide
    
  • 6fv0 – mKLC1 TPR domain + nanobody
    
  • 5ojf – mKLC2 TPR domain
    
  • 3zfw, 5fjy, 6ejn, 6swu - mKLC2 TPR domain + peptide
    

• NOD
  • 3dc4 – DmNOD catalytic core domain+ADP + Mg
    
  • 3dcb - DmNOD catalytic core domain+AMPPNP + Mg
    
  • 3dco - DmNOD catalytic core domain+ cTubulin + ADP + GDP + GTP + Mg
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox, Joel L. Sussman