8sxn: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of NLRP3 and NEK7 complex== | |||
<StructureSection load='8sxn' size='340' side='right'caption='[[8sxn]], [[Resolution|resolution]] 4.04Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8sxn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SXN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.04Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7YN:1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea'>7YN</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sxn OCA], [https://pdbe.org/8sxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sxn RCSB], [https://www.ebi.ac.uk/pdbsum/8sxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sxn ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1.<ref>PMID:17101132</ref> <ref>PMID:17586473</ref> <ref>PMID:19414596</ref> | ||
[[Category: Lindahl | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Pietrak | [[Category: Large Structures]] | ||
[[Category: | [[Category: Bottelbergs A]] | ||
[[Category: Sharma | [[Category: Grauwen K]] | ||
[[Category: | [[Category: Haloi N]] | ||
[[Category: | [[Category: Lindahl E]] | ||
[[Category: | [[Category: Matico RE]] | ||
[[Category: | [[Category: Miller R]] | ||
[[Category: Oehlrich D]] | |||
[[Category: Opdenbosch NV]] | |||
[[Category: Perez-Benito L]] | |||
[[Category: Pietrak B]] | |||
[[Category: Schoubroeck BV]] | |||
[[Category: Sharma S]] | |||
[[Category: Suarez J]] | |||
[[Category: Tresadern GJ]] | |||
[[Category: Yin Y]] | |||
[[Category: Yu X]] | |||
Latest revision as of 07:21, 14 February 2024
Structure of NLRP3 and NEK7 complex
| ||||||||||||