Prestin

spinqualitylabelsall models Rat prestin STAS domain complex with Cl- ion and ethylene glycol (PDB code 5euu) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Prestin (Pre) is a motor protein found in the outer hair cells of the cochlea. It is essential for mammalian hearing. Pre is a membranal anion transporter. See STAS domain of the SLC26 anion transporter prestin. Disease Mutations in Pre are associated with non-syndromic hearing loss. Structural highlights Pre C-terminal is mainly composed of a STAS (Sulfate Transporters and Anti-Sigma factor antagonist) domain. 1st Cl coordination site. Water molecules are shown as red spheres. 2nd Cl coordination site.

3D Structures of prestin

Updated on 13-July-2026

STAS domain of the SLC26 anion transporter prestin, 7lgw, 7lh3, 7v73, 7v74 – hPre – human – Cryo EM
7lh2, 7v75 – hPre + salicylate – Cryo EM
3llo – rPre STAS domain – rat
5eus – rPre STAS domain + Br
5euu – rPre STAS domain + Cl
5euz – rPre STAS domain + I
5euw – rPre STAS domain + NO3
5eux – rPre STAS domain + CNS
7sun – Pre – gerbil – Cryo EM
5ezb – Pre STAS domain - chicken
7s8x, 7s9b, 7s9c, 7s9d, 8uc1 – dPre – dolphin – Cryo EM
7s9a, 7s9e – dPre + salicylate – Cryo EM

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