Proliferating cell nuclear antigen 3D structures

3D Structures of Proliferating Cell Nuclear Antigen

Updated on 19-July-2026

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• Unliganded PCNA
  • 1vym, 1w60, 3vkx, 6fcm, 8gcj – hPCNA - human
    
  • 3ja9 – hPCNA – Cryo EM
    
  • 5e0t, 5mom, 8e84 – hPCNA (mutant)
    
  • 1plq, 1plr, 3lox, 4yhr, 5t9d – yPCNA - yeast
    
  • 3f1w, 3f1x, 3gpm, 3gpn, 4l60, 4l6p, 5v7m, 5v7l, 5v7k, 6cx2, 6cx3, 6cx4, 6d0q, 6d0r, 6w9w, 6wac - yPCNA (mutant)
    
  • 3l0x - yPCNA N fragment + C fragment
    
  • 2hii, 2hik, 2ix2, 2ixi - SsPCNA A + PCNA B + PCNA C
    
  • 2nti - SsPCNA A + PCNA B (mutant) + PCNA C
    
  • 2ijx - SsPCNA A
    
  • 1ge8, 1iz4, 1iz5, 5auj – PfPCNA (mutant) - Pyrococcus furiosus
    
  • 3hi8, 3ifv - PCNA - Haloferax volcanii
    
  • 3aix, 3aiz - StPCNA B + PCNA C – Sulfolobus tokodaii
    
  • 1ud9 – StPCNA – Sulfolobus tokodaii
    
  • 3p91 – PCNA – Entamoeba histoytiica
    
  • 4hk1 – PCNA – Drosophila melanogaster
    
  • 4cs5 – PCNA – Litopenaeus vannamei
    
  • 5cfk, 5h0t, 5hac, 7wp3 - PCNA - Leishmania donovani
    
  • 1rwz – AfPCNA - Archaeglobus fulgidus
    
  • 3lx1 - TkPCNA1 - Thermococcus kodakarensis
    
  • 5a6d - PCNA - Thermococcus gammatolerans
    
  • 7ep8 – PCNA – Neurospora crassa
    
  • 7bup – PCNA – Candida albicans
    
  • 7n5i, 7n5j, 7n5k, 7n5l, 7n5m, 7n5n – PCNA – Thermococcus gammatolerans
    
  • 6j0j – LdPCNA – Leishmania donovani
    
  • 5tup – AfPCNA – Aspergillus fumigatus
    
  • 7o1e – CtPCNA – Chaetomium thermophilum
    
  • 7ype, 7ypf – PCNA – African swine fever virus
    
• PCNA + Dpo
  • 6hvo - hPCNA + hDpo δ
    
  • 6s1m, 6s1n, 6s1o, 6tny, 6tnz - hPCNA + hDpo δ + DNA – Cryo EM
    
  • 2zvk – hPCNA + hDpo ε
    
  • 2zvl – hPCNA + hDpo κ
    
  • 7nv0, 7nv1 - hPCNA + hDpo κ + DNA – Cryo EM
    
  • 2zvm – hPCNA + hDpo τ
    
  • 7kc0 - yPCNA + yDpo δ + DNA – Cryo EM
    
  • 3fds – SsPCNA B + PCNA C + SsDpo IV
    
  • 3a2f - PfPCNA + Dpo
    
• PCNA complexes with peptide
  • 1vyj, 1u76, 1u7b, 4rjf, 4ztd, 5iy4, 5mav, 5mlo, 5mlw, 5yco, 5yd8, 6cbi, 6fcn, 7kq0, 7kq1, 7m5l, 7m5m, 7m5n, 8cob, 9vgw – hPCNA + peptide
  • 5e0u - hPCNA (mutant) + peptide
    
  • 4d2g, 6gws – hPCNA + p15 peptide
    
  • 6e49, 8fsq – hPCNA + DNA helicase peptide
    
  • 6eht – hPCNA + p15 peptide + DNA
    
  • 5e0v - hPCNA + Flap structure-specific endonuclease peptide
    
  • 6qcg – hPCNA + CDT1 peptide
    
  • 6qc0 – hPCNA + CDT2 peptide
    
  • 6k3a – hPCNA + DNMT1 peptide
    
  • 6e49 – hPCNA + PIF-1 peptide
    
  • 6cbi – hPCNA + peptide inhibitor
    
  • 6gws – hPCNA + PCNA-associated factor peptide
    
  • 6eht – hPCNA + PCNA-associated factor peptide + DNA
    
  • 6o09 – AtPCNA + peptide
    
  • 1rxm – AfPCNA + Flap endonuclease-1 peptide
    
  • 2od8, 5zut – yPCNA + peptide
    
  • 8thw – yPCNA + CAC1 PIM motif
    
  • 6qh1 – PCNA + SPD1 peptide – fission yeast
    
  • 7o1f, 8p9o, 8q7i – CtPCNA + peptide
    
  • 8gj5, 8gjf – AfPCNA + peptide
    
• PCNA complexes with protein
  • 7efa – hPCNA + adenine DNA glycosylase
    
  • 1axc – hPCNA + P21/WAF1 C-terminal
    
  • 1ul1 – hPCNA + Flap endonuclease-1
    
  • 8yjh, 8yjl, 8yjq, 8yjr, 8yjs, 8yju, 8yjv, 8yjw, 8yjz – hPCNA + Flap endonuclease-1 + DNA – Cryo EM
    
  • 3p87 – hPCNA + RNase H2 subunit B (mutant)
    
  • 3tbl - hPCNA + ubiquitin
    
  • 8b8t - hPCNA + DNA ligase 1 – Cryo EM
    
  • 7qnz - hPCNA + DNA ligase 1 + DNA – Cryo EM
    
  • 7qo1 - hPCNA + DNA ligase 1 + flap endonuclease + DNA – Cryo EM
    
  • 6vvo – hPCNA + replication factors 1-5 – Cryo EM
    
  • 7u19, 7u1a, 7u1p – hPCNA + replication factors 1-5 + DNA – Cryo EM
    
  • 8umt, 8umu, 9iin– hPCNA + replication factors 1-5 + CTF18 – Cryo EM
    
  • 8umv, 8umw, 8umy, 8un0 – hPCNA + replication factors 1-5 + CTF18 + DNA – Cryo EM
    
  • 8zwo, 9uiq – hPCNA + replication factors 1-5 + CTF18 + DNA + ADP + ATP – Cryo EM
    
  • 8ui7, 8ui8, 8ui9, 8uii – hPCNA + replication factors 1-5 + ATAD5 – Cryo EM
    
  • 9b8s, 9b8t, 9f6d, 9f6e, 9f6f, 9ne6, 9ne7, 9ne8, 9ne9, 9nea, 9sri – hPCNA + DNA polymerase epsilon + DNA – Cryo EM
    
  • 9chm – hPCNA + FAN1 – Cryo EM
    
  • 9cg4, 9cl7, 9cma, 9eoa, 9gy0 – hPCNA + FAN1 + DNA – Cryo EM
    
  • 2zvv – AtPCNA A + cyclin-dependent kinase inhibitor 1 peptide – Arabidopsis thaliana
  • 7thj, 7thv, 7ti8, 7tic, 7tku – yPCNA + replication factors 1-5 – Cryo EM
    
  • 7tfh, 7tfi, 7tfj, 7tib, 7tid, 8dqx, 8dqz, 8dr0, 8dr1, 8dr3, 8dr4, 8dr5, 8dr6, 8dr7 – yPCNA + replication factors 1-5 + DNA – Cryo EM
    
  • 8thc, 8thd – yPCNA + replication factors 1-5 + ELG1 – Cryo EM
    
  • 8tw7 – yPCNA + replication factors 1-5 + CTF18 – Cryo EM
    
  • 8twb – yPCNA + replication factors 1-5 + CTF18 + DNA – Cryo EM
    
  • 8twa – yPCNA + replication factors 1-5 + CTF18 + CTF8 + DNA polymerase epsilon + DCC1 + DNA – Cryo EM
    
  • 3l0w, 3l10 - yPCNA + monoubiquinated PCNA
    
  • 1sxj – yPCNA + replication factor C
    
  • 3v60, 3v61 – yPCNA (mutant) + ubiquitin-like protein SMT3
    
  • 5jne - yPCNA (mutant) + ubiquitin-like protein SMT3 + UBC9
    
  • 3v62 – yPCNA (mutant) + ubiquitin-like protein SMT3 + ATP-dependent DNA helicase SRS2
    
  • 3pge - yPCNA N fragment + SUMO-C fragment
    
  • 2io4 – SsPCNA B (mutant) + PCNA C - Sulfolobus solfataricus
    
  • 2izo - SsPCNA B + PCNA C + Flap structure-specific endonuclease
    
  • 1isq - PfPCNA (mutant) + replication factor C large subunit
    
  • 3p83 - AfPCNA + RNase HII
    
  • 1rxz - AfPCNA + Flap structure-specific endonuclease
    
  • 5da7 - TkPCNA + protein inhibitor
    
• PCNA complexes with smaller molecules
  • 3wgw, 8gl9, 8gla, 9n3l, 9o6r – hPCNA + inhibitor
    
  • 6gis – hPCNA + DNA
    
  • 3k4x - yPCNA + DNA
    
  • 6k2m – LdPCNA + Arg
    
• PCNA homolog or DNA polymerase sliding clamp
  • 6knb, 6knc - TkPCNA + Dpo II + DNA – Cryo EM
    
  • 5dai – TkPCNA + FEN-1 peptide
    
  • 6t7x – PaPCNA – Pyrococcus abyssi
    
  • 6t7y – PaPCNA + DP2 peptide
    
  • 8ppt, 8ppv – PaPCNA + DNA polymerase D + DP2 peptide + DNA
    
  • 6t8h - PaPCNA + Dpo II + DNA – Cryo EM
    
  • 6aig, 24ku – PCNA – Aeropyrum pernix
    
  • 7rpo, 7rpw, 7rpx – SsPCNA A + PCNA B + PCNA C + DNA ligase + DNA – Cryo EM
    
• PCNA homolog 2 or DNA polymerase sliding clamp 2 or PCNA2 or PCNA B
  • 3lx2 – TkPCNA2
    
  • 24jd – ApPCNA2
    
  • 2zvw – AtPCNA B + cyclin-dependent kinase inhibitor 1 peptide – Arabidopsis thaliana

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman