9c24: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9c24 is ~~ON HOLD~~

==Fab F946 in complex with OspCB==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9c24]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C24 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c24 OCA], [https://pdbe.org/9c24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c24 RCSB], [https://www.ebi.ac.uk/pdbsum/9c24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c24 ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/OSPC2_BORBG OSPC2_BORBG] Major immunodominant protein in mammalian hosts. Required for initial stages of mammalian infection. Inhibits macrophage-mediated phagocytosis of the bacteria. Binds human plasminogen; this probably confers an extracellular protease activity on the bacteria that allows it to traverse tissue. Interaction with tick I.ricinus salivary protein Salp15 protects the bacteria from antibody-mediated killing in vitro and in vivo.[UniProtKB:Q07337]

__TOC__

</StructureSection>

[[Category: Borreliella burgdorferi B31]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Mantis N]]

[[Category: Rudolph MJ]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9c24 is ON HOLD
+==Fab F946 in complex with OspCB==
+<StructureSection load='9c24' size='340' side='right'caption='[[9c24]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9c24]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C24 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c24 OCA], [https://pdbe.org/9c24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c24 RCSB], [https://www.ebi.ac.uk/pdbsum/9c24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c24 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OSPC2_BORBG OSPC2_BORBG] Major immunodominant protein in mammalian hosts. Required for initial stages of mammalian infection. Inhibits macrophage-mediated phagocytosis of the bacteria. Binds human plasminogen; this probably confers an extracellular protease activity on the bacteria that allows it to traverse tissue. Interaction with tick I.ricinus salivary protein Salp15 protects the bacteria from antibody-mediated killing in vitro and in vivo.[UniProtKB:Q07337]
+__TOC__
+</StructureSection>
+[[Category: Borreliella burgdorferi B31]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Mantis N]]
+[[Category: Rudolph MJ]]