9jxv: Difference between revisions
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==human translocase of the outer mitochondrial membrane (TOM complex)== | |||
<StructureSection load='9jxv' size='340' side='right'caption='[[9jxv]], [[Resolution|resolution]] 2.89Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9jxv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JXV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.89Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jxv OCA], [https://pdbe.org/9jxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jxv RCSB], [https://www.ebi.ac.uk/pdbsum/9jxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jxv ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/TOM40_HUMAN TOM40_HUMAN] Early-onset autosomal dominant Alzheimer disease. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TOM40_HUMAN TOM40_HUMAN] Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022).<ref>PMID:15644312</ref> <ref>PMID:31206022</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Wang WH]] | |||
[[Category: Yang MJ]] | |||
Latest revision as of 07:10, 15 October 2025
human translocase of the outer mitochondrial membrane (TOM complex)
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