9kcc: Difference between revisions

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'''Unreleased structure'''


The entry 9kcc is ON HOLD  until Paper Publication
==DNA duplex containing copper-mediated 5-fluorouracil-cytosine base pairs==
<StructureSection load='9kcc' size='340' side='right'caption='[[9kcc]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9kcc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KCC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=UFP:5-FLUORO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>UFP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kcc OCA], [https://pdbe.org/9kcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kcc RCSB], [https://www.ebi.ac.uk/pdbsum/9kcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kcc ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Only mercury(II) and silver(I) ions are known to specifically bind to natural and naturally modified base pairs in duplex DNA to form metal-mediated base pairs. We found novel, specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil (FdU) in duplex DNA, forming C-Cu-FdU and FdU-Cu-C base pairs.


Authors: Kondo, J., Hirabayashi, K., Torigoe, H., Adachi, S.
Novel specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil in duplex DNA.,Torigoe H, Hirabayashi K, Adachi S, Kondo J Dalton Trans. 2025 May 6;54(18):7208-7213. doi: 10.1039/d5dt00619h. PMID:40265694<ref>PMID:40265694</ref>


Description: DNA duplex containing copper-mediated 5-fluorouracil-cytosine base pairs
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Adachi, S]]
<div class="pdbe-citations 9kcc" style="background-color:#fffaf0;"></div>
[[Category: Torigoe, H]]
== References ==
[[Category: Kondo, J]]
<references/>
[[Category: Hirabayashi, K]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Adachi S]]
[[Category: Hirabayashi K]]
[[Category: Kondo J]]
[[Category: Torigoe H]]
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