9oeg: Difference between revisions
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==Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2== | |||
<StructureSection load='9oeg' size='340' side='right'caption='[[9oeg]], [[Resolution|resolution]] 3.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9oeg]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Astrovirus_VA1 Astrovirus VA1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OEG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9oeg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9oeg OCA], [https://pdbe.org/9oeg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9oeg RCSB], [https://www.ebi.ac.uk/pdbsum/9oeg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9oeg ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CAPSD_HASVA CAPSD_HASVA] The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the immature VP70 virion.[UniProtKB:Q9IFX1] Self-assembles to form an icosahedral capsid with a T=3 symmetry, about 43 nm in diameter.[UniProtKB:O12792] Forms the spikes at the surface of the virion (PubMed:38416796). Plays a role in the attachment to target host cell (By similarity).[UniProtKB:O12792]<ref>PMID:38416796</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Astrovirus VA1]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Balasco Serrao VH]] | |||
[[Category: DuBois RM]] | |||
[[Category: Dzimianski JV]] | |||
[[Category: Ghosh A]] | |||
Latest revision as of 07:21, 8 July 2026
Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2
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