9jvq: Difference between revisions
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==Yeast Mitochondrial PORIN complex== | |||
<StructureSection load='9jvq' size='340' side='right'caption='[[9jvq]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9jvq]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JVQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jvq OCA], [https://pdbe.org/9jvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jvq RCSB], [https://www.ebi.ac.uk/pdbsum/9jvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jvq ProSAT]</span></td></tr> | ||
[[Category: Akihisa | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/VDAC1_YEAST VDAC1_YEAST] Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane (PubMed:9435273). The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (PubMed:9435273). The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:9435273). Is the major permeability factor of the mitochondrial outer membrane (PubMed:9435273).<ref>PMID:9435273</ref> Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids.<ref>PMID:38065946</ref> | ||
[[Category: Takeda | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Akihisa T]] | |||
[[Category: Endo T]] | |||
[[Category: Kikkawa M]] | |||
[[Category: Takeda H]] | |||
Latest revision as of 08:20, 13 August 2025
Yeast Mitochondrial PORIN complex
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