9vko: Difference between revisions

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'''Unreleased structure'''


The entry 9vko is ON HOLD  until 2027-06-23
==CryoEM struccture of the type III secretion system gatekeeper protein InvE by cryo-electron microscopy.==
 
<StructureSection load='9vko' size='340' side='right'caption='[[9vko]], [[Resolution|resolution]] 3.07&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9vko]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VKO FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.07&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vko OCA], [https://pdbe.org/9vko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vko RCSB], [https://www.ebi.ac.uk/pdbsum/9vko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vko ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INVE_SALTY INVE_SALTY] Involved in the triggering of intracellular events that lead to microbial internalization. These events include increase in calcium level, redistribution of actin microfilaments, and changes in the normal structure of the microvilli. Encoded within the type III secretion system (SPI-1 T3SS), it is essential for the translocation of protein effectors into host cells. Forms a complex with SipB and SipC in the presence of their chaperone SicA. Positively regulates the secretion of SPI-1 T3SS effector proteins SipB, SipC and SipD and negatively influences the secretion of SipA, SopA and SptP.<ref>PMID:12169593</ref> <ref>PMID:1631083</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Cheng XQ]]
[[Category: Jiang WX]]
[[Category: Wu M]]
[[Category: Xing Q]]
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