9o4g: Difference between revisions

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'''Unreleased structure'''


The entry 9o4g is ON HOLD
==Cryo-EM structure of the CHSY3-CHPF1 chondroitin synthase heterodimer==
 
<StructureSection load='9o4g' size='340' side='right'caption='[[9o4g]], [[Resolution|resolution]] 3.42&Aring;' scene=''>
Authors: Tehari, D., Cortiella, N., Perez, C., Moremen, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9o4g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_adenovirus_sp. Human adenovirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9O4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9O4G FirstGlance]. <br>
Description: Cryo-EM structure of the CHSY3-CHPF1 chondroitin synthase heterodimer
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.42&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
[[Category: Moremen, K]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9o4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9o4g OCA], [https://pdbe.org/9o4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9o4g RCSB], [https://www.ebi.ac.uk/pdbsum/9o4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9o4g ProSAT]</span></td></tr>
[[Category: Perez, C]]
</table>
[[Category: Tehari, D]]
== Function ==
[[Category: Cortiella, N]]
[https://www.uniprot.org/uniprot/CHSS3_HUMAN CHSS3_HUMAN] Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.<ref>PMID:12907687</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human adenovirus sp]]
[[Category: Large Structures]]
[[Category: Cortiella N]]
[[Category: Moremen K]]
[[Category: Perez C]]
[[Category: Tehari D]]