9o4g: Difference between revisions
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==Cryo-EM structure of the CHSY3-CHPF1 chondroitin synthase heterodimer== | |||
<StructureSection load='9o4g' size='340' side='right'caption='[[9o4g]], [[Resolution|resolution]] 3.42Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9o4g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_adenovirus_sp. Human adenovirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9O4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9O4G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.42Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9o4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9o4g OCA], [https://pdbe.org/9o4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9o4g RCSB], [https://www.ebi.ac.uk/pdbsum/9o4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9o4g ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CHSS3_HUMAN CHSS3_HUMAN] Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.<ref>PMID:12907687</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human adenovirus sp]] | |||
[[Category: Large Structures]] | |||
[[Category: Cortiella N]] | |||
[[Category: Moremen K]] | |||
[[Category: Perez C]] | |||
[[Category: Tehari D]] | |||