Phospholipase C: Difference between revisions
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== Function == | == Function == | ||
'''Phospholipase C''' (PLC) cleaves phospholipids before the phosphate group. PLCs catalyze the conversion of phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5-trisphosphate and diacylglycerol.<ref>PMID:12054652</ref> | '''Phospholipase C''' (PLC) or '''1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma''' cleaves phospholipids before the phosphate group. PLCs catalyze the conversion of phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5-trisphosphate and diacylglycerol.<ref>PMID:12054652</ref> | ||
*'''Phospholipase C β''' is a key enzyme in mammalian taste signal transduction<ref>PMID:15210203</ref>. For more details on phospholipase C β see [[PLC beta 3 Gq]]. | *'''Phospholipase C β''' is a key enzyme in mammalian taste signal transduction<ref>PMID:15210203</ref>. For more details on phospholipase C β see [[PLC beta 3 Gq]]. | ||
*'''Phospholipase C γ''' is a physiological guanine nucleotide exchange factor for the nuclear GTPase<ref>PMID:11823862</ref>. | *'''Phospholipase C γ''' is a physiological guanine nucleotide exchange factor for the nuclear GTPase<ref>PMID:11823862</ref>. | ||
