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New page: left|200px<br /><applet load="1hmj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1hmj" /> '''SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT...
 
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[[Image:1hmj.gif|left|200px]]<br /><applet load="1hmj" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:1hmj.gif|left|200px]]<br /><applet load="1hmj" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="1hmj" />
caption="1hmj" />
'''SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H'''<br />
'''SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H'''<br />


==Overview==
==Overview==
The archaeal H and eukaryotic RPB5 RNA polymerase subunits are highly, homologous and are likely to play a fundamental role in transcription that, extends from archaea to humans. We report the structure of subunit H, in, solution, from the archaeon Methanococcus jannaschii using, multidimensional nuclear magnetic resonance. The structure reveals a novel, fold containing a four-stranded mixed beta sheet that is flanked on one, side by three short helices. The dominant feature is beta-ribbon motif, which presents a hydrophobic, basic surface, and defines a general RNA, polymerase architectural scaffold.
The archaeal H and eukaryotic RPB5 RNA polymerase subunits are highly homologous and are likely to play a fundamental role in transcription that extends from archaea to humans. We report the structure of subunit H, in solution, from the archaeon Methanococcus jannaschii using multidimensional nuclear magnetic resonance. The structure reveals a novel fold containing a four-stranded mixed beta sheet that is flanked on one side by three short helices. The dominant feature is beta-ribbon motif, which presents a hydrophobic, basic surface, and defines a general RNA polymerase architectural scaffold.


==About this Structure==
==About this Structure==
1HMJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HMJ OCA].  
1HMJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HMJ OCA].  


==Reference==
==Reference==
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[[Category: subunit h]]
[[Category: subunit h]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:02:47 2008''